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Merck
CN

91C

Sigma-Aldrich

白细胞氯乙酸AS-D萘酚酯(特异性酯酶)试剂盒

别名:

Leder染色

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About This Item

UNSPSC代码:
12352106
NACRES:
NA.47

描述

Kit formulated with all liquid reagents

质量水平

保质期

Expiry date on the label.

IVD

for in vitro diagnostic use

应用

hematology
histology

运输

wet ice

储存温度

2-8°C

应用

酯酶普遍存在于自然界中,其中包含了一系列不同的酶,均可作用于选定底物。使用91C 试剂盒可通过“特定酯酶”对萘酚AS-D氯乙酸盐进行酶促水解,从而释放出萘酚自由基化合物。它随后可与重氮基化合物进行偶联,在酶活性位点处形成带明显颜色的沉淀。这种酶通常被认为对粒细胞系的细胞具有特异性。也可用于检测外周血、骨髓或经石蜡包埋的组织切片中的中性粒细胞。

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书

  • 915Citrate Solution, pH 3.6±0.1 (25 °C), 27 mM 50 mL化学品安全说明书

  • 912Fast Red Violet LB Base Solution 10 mL化学品安全说明书

  • 911Naphthol AS-D Chloroacetate Solution 10 mL化学品安全说明书

  • 911Naphthol AS-D Chloroacetate Solution 50 mL化学品安全说明书

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1 - Skin Sens. 1 - STOT RE 2 Oral - STOT SE 3

靶器官

Kidney, Respiratory system

补充剂危害

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

法规信息

监管及禁止进口产品

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分析证书(COA)

Lot/Batch Number

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Ganesan Ramesh et al.
Kidney international, 65(2), 490-499 (2004-01-14)
Salicylate was recently shown to provide protection against cisplatin nephrotoxicity in rats. We have demonstrated that enhanced tumor necrosis factor-alpha (TNF-alpha) production mediates, in part, cisplatin nephrotoxicity. The purpose of this study was to determine if the protective effects of
Paramahamsa Maturu et al.
Translational oncology, 7(4), 484-492 (2014-06-28)
The role of inflammation in cancer has been reported in various adult malignant neoplasms. By contrast, its role in pediatric tumors has not been as well studied. In this study, we have identified and characterized the infiltration of various inflammatory
Ralf A Linker et al.
Journal of immunology (Baltimore, Md. : 1950), 180(4), 2204-2213 (2008-02-06)
The neurotrophic cytokines ciliary neurotrophic factor and leukemia inhibitory factor (LIF) play a key role in neuronal and oligodendrocyte survival and as protective factors in neuroinflammation. To further elucidate the potential of endogenous LIF in modulating neuroinflammation, we studied myelin
Tarek M El-Achkar et al.
American journal of physiology. Renal physiology, 300(4), F999-1007 (2011-01-14)
Tamm-Horsfall protein (THP) is a glycoprotein expressed exclusively in thick ascending limbs (TAL) of the kidney. We recently described a novel protective role of THP against acute kidney injury (AKI) via downregulation of inflammation in the outer medulla. Our current
Vittoria Esposito et al.
American journal of physiology. Renal physiology, 304(4), F440-F450 (2012-12-14)
C/EBP homologous protein (CHOP) is an important mediator of endoplasmic reticulum (ER) stress-induced cell and organ injury. Here we show that lipopolysaccharide (LPS)-induced acute kidney injury (AKI) is associated with ER stress and elevated CHOP. We postulated that CHOP(-/-) mice

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