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91553

Sigma-Aldrich

N-Palmitoyl-D-sphingomyelin

≥96.0% (TLC)

别名:

SM(d18:1/16:0), (2S,3R,4E)-2-(Palmitoylamino)-4-octadecene-3-hydroxy-1-phosphocholine, 16:0 SM (d18:1/16:0), N-(Hexadecanoyl)-sphing-4-enine-1-phosphocholine, N-Palmitoyl-D-erythro-sphingosylphosphorylcholine, C16 Sphingomyelin

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About This Item

经验公式（希尔记法）:
C39H79N2O6P
CAS号:
6254-89-3
分子量:
703.03
Beilstein:
4833682
MDL编号:
MFCD02259286
UNSPSC代码:
12352211
PubChem化学物质编号:
329770051
NACRES:
NA.85

质量水平

100

方案

≥96.0% (TLC)

表单

powder or crystals

组成

carbon content, 66.63%
hydrogen content, 11.33%
nitrogen content, 3.98%

杂质

≤6.0 wt. % water

脂质类型

sphingolipids

运输

wet ice

储存温度

−20°C

SMILES字符串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O

InChI

1S/C39H79N2O6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-38(42)37(36-47-48(44,45)46-35-34-41(3,4)5)40-39(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h30,32,37-38,42H,6-29,31,33-36H2,1-5H3,(H-,40,43,44,45)/b32-30+/t37-,38+/m0/s1

InChI key

RWKUXQNLWDTSLO-GWQJGLRPSA-N

相关类别

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
BCCM5509
BCBT2510
BCCJ6123
BCBR9763V
BCBH6562V

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Simone Colombo et al.
Scientific reports, 8(1), 12365-12365 (2018-08-19)
Endothelial dysfunction has been widely associated with oxidative stress, glucotoxicity and lipotoxicity and underlies the development of cardiovascular diseases (CVDs), atherosclerosis and diabetes. In such pathological conditions, lipids are emerging as mediators of signalling pathways evoking key cellular responses as
Atsushi Hori et al.
Clinica chimica acta; international journal of clinical chemistry, 453, 95-99 (2015-11-21)
Sphingomyelin (SM) is a key component of extracellular membranes and lipoproteins, and plays roles in cell signaling and as a component of lipoproteins. SM species differ in terms of fatty acid (FA) composition. However, no simple, rapid, quantitative assay for
Reza Siavashi et al.
Biophysical journal, 117(2), 296-306 (2019-07-08)
Sphingolipids constitute a significant fraction of cellular plasma membrane lipid content. Among sphingolipids, ceramide levels are usually very low. However, in some cell processes like apoptosis, cell membrane ceramide levels increase markedly because of the activation of enzymes like acid
Saskia Klutzny et al.
Cell death & disease, 8(3), e2709-e2709 (2017-03-31)
Owing to lagging or insufficient neo-angiogenesis, hypoxia is a feature of most solid tumors. Hypoxic tumor regions contribute to resistance against antiproliferative chemotherapeutics, radiotherapy and immunotherapy. Targeting cells in hypoxic tumor areas is therefore an important strategy for cancer treatment.
Jin Lu et al.
Angewandte Chemie (International ed. in English), 59(40), 17572-17579 (2020-07-11)
In soft matter, thermal energy causes molecules to continuously translate and rotate, even in crowded environments, thereby impacting the spatial organization and function of most molecular assemblies, such as lipid membranes. Directly measuring the orientation and spatial organization of large
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