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Merck
CN

90878

聚(乙二醇)

greener alternative

BioUltra, 300

别名:

PEG

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关于此项目

线性分子式:
H(OCH2CH2)nOH
化学文摘社编号:
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:
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Quality Level

product line

BioUltra

form

viscous liquid

mol wt

Mr 285-315

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

insoluble matter:, passes filter test, ≤0.001% peroxides (as H2O2):

refractive index

n20/D 1.465

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

density

1.125 g/mL at 20 °C

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: 0.06, λ: 280 nm Amax: 0.03

greener alternative category

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application


  • 基于蜥蜴利什曼原虫的无真核细胞冷冻蛋白表达系统: 该研究探索了聚乙二醇(PEG)在构建无真核细胞冷冻蛋白表达系统中的用途。该研究表明了聚乙二醇促进无系统系统稳定和保藏的方式,增进了各种生化应用中的蛋白合成能力(Alfaro-Palma et al., 2024)。

  • 采用聚乙二醇化镧系复合物的高对比度发光免疫组织化学。: 聚乙二醇化镧系复合物在免疫组织化学法中的应用显著改善了发光信号的对比度和特异性。该创新研究有助于实现更准确的生物化学分析和诊断(Su et al., 2022)。

  • 通过炎症细胞亚群的分层聚类分析对于工程水凝胶的免疫反应i: 该研究考察了组织工程中使用的聚乙二醇基水凝胶的免疫反应。该研究提供了有关生物相容性和炎症反应的见解,这对于先进生物材料的设计至关重要(Fernandez-Yague et al., 2022)。

  • 人特异性生物分子冠调节纳米颗粒与人血中免疫细胞的相互作用该研究显示了纳米颗粒的聚乙二醇化影响其与免疫细胞相互作用的方式,影响了生物化学和分子生物学中的药物递送系统和治疗功效(Ju et al., 2020)。

  • 用于细菌和来源于哺乳细胞的细胞外囊泡表面功能化修饰的后插入策略。: 该论文讨论了利用聚乙二醇进行细胞外囊泡表面功能化修饰的后插入方法,增进了其在靶向药物递送和生物化学研究中的潜力(Jiang et al., 2021)。



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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.
Tine Cuppens et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 23(5), 1274-1285 (2017-02-25)
Vural Tagal et al.
Nature communications, 8, 14098-14098 (2017-01-20)
Mutations in the SMARCA4/BRG1 gene resulting in complete loss of its protein (BRG1) occur frequently in non-small cell lung cancer (NSCLC) cells. Currently, no single therapeutic agent has been identified as synthetically lethal with SMARCA4/BRG1 loss. We identify AURKA activity
Hongge Wang et al.
Oncogene, 39(14), 2905-2920 (2020-02-08)
PARP1 and PARP2 play critical roles in regulating DNA repair and PARP inhibitors have been approved for the treatment of BRCA1/2-mutated ovarian and breast cancers. It has long been known that PARP inhibition sensitizes cancer cells to DNA-damaging cytotoxic agents



全球贸易项目编号

货号GTIN
90878-250ML-F04061838170255
90878-1L-F04061838170248