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主要文件

安全信息

905H-0

Sigma-Aldrich

Cytokeratin 5 (EP1601Y) + Cytokeratin 14 (LL002)

Mouse and Rabbit Monoclonal Antibody

别名:

Cytokeratin 5 (EP1601Y) + Cytokeratin 14 (LL002) Mouse and Rabbit Monoclonal Antibody

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse
rabbit

质量水平

100
500

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

EP1601Y + LL002, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

表单

buffered aqueous solution

种属反应性

human

包装

bottle of 1.0 mL predilute (905H-07)
bottle of 7.0 mL predilute (905H-08)

制造商/商品名称

Cell Marque®

浓度

0.1-1.5 μg/mL (predilute)

同位素/亚型

IgG3
IgG

运输

wet ice

储存温度

2-8°C

基因信息

human ... KRT5(3852)

一般描述

Cytokeratin 5 is an intermediate filament protein of 58 kD molecular wt. amongst the cytokeratin family. It is a type II (basic) cytokeratin. Antibodies to this protein identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium. Cytokeratin 14 is a 50 kD polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-Cytokeratin 5 has been useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelial mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas immunostain with CK5. Anti-CK14 has been demonstrated to be useful in differentiating squamous cell carcinomas from other epithelial tumors. Anti-CK5, along with anti-CK14, has found application in identifying the basaloid phenotype of breast carcinoma, a tumor with poor prognosis.

质量


IVD

IVD

IVD

RUO

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 728-729 (2014)
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 212-212 (2014)
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 212-212 (2014)
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 728-729 (2014)
David J Dabbs et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 19(11), 1506-1511 (2006-08-31)
The basal phenotype of breast carcinoma was demonstrated from a study of gene expression profiles, which demonstrated five carcinoma phenotypes with differing immunohistologic profiles and outcomes. The basal phenotype, so-named because of an immunohistologic profile that is similar to myoepithelial

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