推荐产品
生物来源
mouse
质量水平
100
500
偶联物
unconjugated
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
HMB-45+A103+T311, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
表单
buffered aqueous solution
种属反应性
human
包装
bottle of 1.0 mL predilute (904H-07)
bottle of 7.0 mL predilute (904H-08)
制造商/商品名称
Cell Marque®
同位素/亚型
IgG1κ
IgG1
IgG2a
运输
wet ice
储存温度
2-8°C
一般描述
Anti-HMB-45 identifies immature melanosomes. It shows greater specificity for malignant melanomas and metastatic melanomas. MART-1 (also known as Melan A) is a melanocyte differentiation antigen. It is present in melanocytes of normal skin and retina, nevi and in more than 85% of melanomas. Tyrosinase is an enzyme integral in the process of melanin synthesis, and found in 85% to 90% of malignant melanomas. Given these statistics, this cocktail is ideally suited to detection of melanomas and melanocytic lesions.
质量
 IVD |  IVD |  IVD |  RUO |
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
M L Prasad et al.
The American journal of surgical pathology, 25(6), 782-787 (2001-06-08)
Malignant melanomas of the oral and sinonasal mucosa are rare tumors. Amelanotic variants can, on occasion, be difficult to recognize by routine light microscopy. Immunohistochemical studies may be needed for a final diagnosis. A number of new monoclonal antibodies to
Deepali Gupta et al.
The American journal of surgical pathology, 26(11), 1450-1457 (2002-11-01)
Malignant melanomas of the vagina are rare tumors. In this study we present the clinicopathologic features and immunohistochemical analysis of 26 such cases seen in our institution over a period of 30 years. The patients' age ranged from 38 to
Guy Orchard
British journal of biomedical science, 59(4), 196-202 (2003-02-08)
Incidence of malignant melanoma (MM) is rising rapidly throughout the Western world, and the number of melanocytic lesions removed for histological assessment has increased. MM can present with a myriad of histological appearances that make diagnosis problematic, particularly when dealing
L Vaggelli et al.
Tumori, 86(4), 346-348 (2000-10-04)
Elective lymph node dissection (ELND) for patients with malignant melanoma is still controversial. A possible alternative could be biopsy of the first tumor draining lymph node, the sentinel node (SN), which can be identified by means of radionuclide techniques. Our
T J de Vries et al.
The Journal of pathology, 193(1), 13-20 (2001-02-13)
With the recent availability of novel antibodies against melanoma antigens tyrosinase and MART-1, it is important to validate their usefulness in pathology practice and in screening patients for immunotherapy treatment. In the present study conducted by the Melanoma Cooperative Group
商品
IHC antibodies enhance dermatopathology beyond H&E stained slides, improving techniques and applications for dermatological research.
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