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Merck
CN

90081

Sigma-Aldrich

3-O-甲基槲皮素

≥97% (HPLC)

别名:

5,7,3′ ,4′ -四羟基-3-甲氧基黄酮, 槲皮素3-O-甲醚

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About This Item

经验公式(希尔记法):
C16H12O7
CAS号:
分子量:
316.26
Beilstein:
324509
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.32

质量水平

检测方案

≥97% (HPLC)

形式

powder

SMILES字符串

COC1=C(Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3

InChI

1S/C16H12O7/c1-22-16-14(21)13-11(20)5-8(17)6-12(13)23-15(16)7-2-3-9(18)10(19)4-7/h2-6,17-20H,1H3

InChI key

WEPBGSIAWZTEJR-UHFFFAOYSA-N

生化/生理作用

3-O-甲基槲皮素能显著抑制环状单磷酸腺苷(cAMP-)和环状单磷酸鸟苷(cGMP-)磷酸二酯酶活性。它具有抗炎、抗支气管扩张的特性,可用于治疗哮喘。它抑制总的炎症细胞、肿瘤坏死因子-α(TNF-α),并减弱白介素的产生。
3-O-甲基槲皮素是黄酮和黄酮生物合成中的代谢产物。它是存在于各种植物中的天然化合物,具有强大的抗癌、抗氧化、抗过敏和抗微生物活性,对番茄环斑病毒具有很强的抗病毒活性

包装

无底玻璃瓶。内含物在插入的融合锥体内。

象形图

Skull and crossbones

警示用语:

Danger

危险声明

预防措施声明

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Hyang Dok-Go et al.
Brain research, 965(1-2), 130-136 (2003-02-20)
The flavonoids quercetin, (+)-dihydroquercetin, and quercetin 3-methyl ether were isolated from the ethyl acetate fractions of the fruits and stems of Opuntia ficus-indica var. saboten. In the present study, we evaluated their protective effects against oxidative neuronal injuries induced in
L Van Puyvelde et al.
Journal of natural products, 52(3), 629-633 (1989-05-01)
3,5-Dihydroxy-6,7,8-trimethoxyflavone, 3-O-methylquercetin, and helichrysetin were isolated from the flowers of the Rwandese medicinal plant, Helichrysum odoratissimum. Because of inconsistencies of the mp of the latter chalcone, a synthesis of helichrysetin was developed. 3-O-Methylquercetin was shown to be an active principle
Mechanisms of suppression of nitric oxide production by 3-O-methylquercetin in RAW 264.7 cells
Jiang JS, et al.
Journal of Ethnopharmacology, 103(2), 281-287 (2006)
Clement K Ameho et al.
The Journal of nutritional biochemistry, 19(7), 467-474 (2007-10-02)
Dietary antioxidants interact in a dynamic fashion, including recycling and sparing one another, to decrease oxidative stress. Limited information is available regarding the interrelationships in vivo between quercetin and vitamin E. We investigated the antioxidant activity and metabolism of quercetin
C Angeloni et al.
Biochimie, 89(1), 73-82 (2006-10-19)
The aim of this study was to investigate the potential of quercetin and two of its "in vivo" metabolites, 3'-O-methyl quercetin and 4'-O-methyl quercetin, to protect H9c2 cardiomyoblasts against H(2)O(2)-induced oxidative stress. As limited data are available regarding the potential

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