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About This Item
经验公式（希尔记法）:
C20H14N2O3 · HCl
CAS号:
分子量:
366.80
Beilstein:
4631860
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.32
推荐产品
产品线
BioReagent
质量水平
方案
≥99.0% (UV)
表单
crystals
mp
>300 °C (lit.)
溶解性
ethanol: soluble
methanol: soluble
荧光
λex 498 nm; λem 520 nm in methanol
适用性
suitable for fluorescence
SMILES字符串
Cl.Nc1ccc2c(OC3=CC(=N)C=CC3=C2c4ccccc4C(O)=O)c1
InChI
1S/C20H14N2O3.ClH/c21-11-5-7-15-17(9-11)25-18-10-12(22)6-8-16(18)19(15)13-3-1-2-4-14(13)20(23)24;/h1-10,21H,22H2,(H,23,24);1H
InChI key
JNGRENQDBKMCCR-UHFFFAOYSA-N
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相关类别
一般描述
罗丹明110或R110是一种三苯甲烷染料，可发射出强烈的绿色荧光。能发出高强度荧光是由于存在作为给电子基团的氨基。罗丹明110的最大激发光谱和发射光谱分别为502.4/521.6521.6 nm。
应用
罗丹明110被用于测定具有准确的动力学参数的蛋白酶活性。它被用于测量诱导细胞凋亡的半胱天冬酶活性。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Xian Zhang et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 59(8), 1667-1672 (2003-05-09)
A simple and sensitive fluorescence quenching method for the determination of trace nitrite has been developed. The method is based on the reaction of Rhodamine 110 with nitrite in acidic medium to form a new compound, which has much lower
P-O Gendron et al.
Journal of fluorescence, 18(6), 1093-1101 (2008-04-24)
Rhodamine derivatives are popular, photostable fluorophores that are used in a number of fluorescent based techniques, including fluorescence correlation spectroscopy (FCS). Indeed, in FCS, both rhodamine 6G (R6G) and rhodamine 110 (R110) are used as calibration standards to determine the
Melissa M Yatzeck et al.
Bioorganic & medicinal chemistry letters, 18(22), 5864-5866 (2008-07-04)
A derivative of rhodamine 110 has been designed and assessed as a probe for cytochrome P450 activity. This probe is the first to utilize a 'trimethyl lock' that is triggered by cleavage of an ether bond. In vitro, fluorescence was
Marcos M Pires et al.
Organic letters, 10(5), 837-840 (2008-02-09)
Glutathione is a crucial component of the redox homeostasis of cells, and altered levels have been linked to human pathologies. We constructed a latent fluorophore (RhoSS) that responds to cellular thiols in vitro and in cyto following intracellular reduction by
H Hug et al.
Biochemistry, 38(42), 13906-13911 (1999-10-21)
Caspases (cysteine aspartate-specific proteases) are a structurally related group of cysteine proteases that cleave peptide bonds following specific recognition sequences. They play a central role in activating apoptosis of vertebrate cells. To measure apoptosis induced by various stimuli and at
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