所有图片(1)
About This Item
经验公式(希尔记法):
C16H13NO4
CAS号:
分子量:
283.28
Beilstein:
1140868
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.32
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方案
≥95% (TLC)
表单
powder or crystals
mp
136-138 °C (lit.)
溶解性
DMF: soluble
DMSO: soluble
alcohols: soluble
荧光
λex 500 nm; λem 593 nm in 0.1 M phosphate pH 8.0 (lipase)
λex 540 nm; λem 590 nm in DMSO
适用性
suitable for fluorescence
储存温度
2-8°C
SMILES字符串
CCCC(=O)Oc1ccc2N=C3C=CC(=O)C=C3Oc2c1
InChI
1S/C16H13NO4/c1-2-3-16(19)20-11-5-7-13-15(9-11)21-14-8-10(18)4-6-12(14)17-13/h4-9H,2-3H2,1H3
InChI key
RGJTZDRUTUWWTD-UHFFFAOYSA-N
应用
suitable as fluorogenic substrate for lipases, choline esterases
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Mapping substrate selectivity of lipases from thermophilic fungi
Journal of Molecular Catalysis. B, Enzymatic, 49, 104-112 (2007)
Christopher M Goins et al.
Biochemistry, 57(16), 2383-2393 (2018-03-31)
Tetrahydrolipstatin (THL) is a covalent inhibitor of many serine esterases. In mycobacteria, THL has been found to covalently react with 261 lipid esterases upon treatment of Mycobacterium bovis cell lysate. However, the covalent adduct is considered unstable in some cases
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