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经验公式(希尔记法):
C16H13NO4
化学文摘社编号:
分子量:
283.28
UNSPSC Code:
12352202
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1140868
产品名称
Resorufin butyrate, suitable for fluorescence, ≥95% (TLC)
InChI
1S/C16H13NO4/c1-2-3-16(19)20-11-5-7-13-15(9-11)21-14-8-10(18)4-6-12(14)17-13/h4-9H,2-3H2,1H3
SMILES string
CCCC(=O)Oc1ccc2N=C3C=CC(=O)C=C3Oc2c1
InChI key
RGJTZDRUTUWWTD-UHFFFAOYSA-N
assay
≥95% (TLC)
form
powder or crystals
mp
136-138 °C (lit.)
solubility
DMF: soluble
DMSO: soluble
alcohols: soluble
fluorescence
λex 500 nm; λem 593 nm in 0.1 M phosphate pH 8.0 (lipase)
λex 540 nm; λem 590 nm in DMSO
suitability
suitable for fluorescence
storage temp.
2-8°C
Application
suitable as fluorogenic substrate for lipases, choline esterases
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Mapping substrate selectivity of lipases from thermophilic fungi
Journal of Molecular Catalysis. B, Enzymatic, 49, 104-112 (2007)
Christopher M Goins et al.
Biochemistry, 57(16), 2383-2393 (2018-03-31)
Tetrahydrolipstatin (THL) is a covalent inhibitor of many serine esterases. In mycobacteria, THL has been found to covalently react with 261 lipid esterases upon treatment of Mycobacterium bovis cell lysate. However, the covalent adduct is considered unstable in some cases
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