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一般描述
醛脱氢酶(ALDH)家族包含19个人类基因。它同时位于细胞核、细胞质、线粒体和内质网上。
应用
面包酵母来源的醛脱氢酶已用于通过Tottmars方法测定醛脱氢酶活性，以确定血清样品中烟酰胺腺嘌呤二核苷酸(NADH)含量变化。它还用于丙酮酸脱羧酶测定。
生化/生理作用
醛脱氢酶(ALDH)是参与非P450醛还原酶系统的关键酶之一。它可以保护细胞免受有毒物质影响。目前确知ALDH的表达水平随肺癌严重程度增加。ALDH可降低因心肌梗塞或心脏手术术后引起的心脏缺血程度。这一基因突变引起的导致Sjogren-Larsson综合征是一种常染色体疾病。
醛脱氢酶催化醛氧化生为羧酸。
包装
无底玻璃瓶。内容物在插入式融锥内。
单位定义
1U相当于每分钟氧化1 μmol乙醛（货号00070）生成乙酸(pH8.0,25℃)所需的酶量。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
Effect of the mixture of Pueraria lobata and Sorbus commixta extract on the alcohol-induced hangover in rats
Hong SC, et al.
Natural Product Sciences, 21(2), 98-103 (2015)
Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer
Jiang F, et al.
Molecular Cancer Research, 7(3), 330-338 (2009)
Thiamine synthesis regulates the fermentation mechanisms in the fungus Aspergillus nidulans
Shimizu M, et al.
Bioscience, Biotechnology, and Biochemistry, 80(9), 1768-1775 (2016)
David W Crabb et al.
The Proceedings of the Nutrition Society, 63(1), 49-63 (2004-04-22)
Alcohol dehydrogenase (ADH) and mitochondrial aldehyde dehydrogenase (ALDH2) are responsible for metabolizing the bulk of ethanol consumed as part of the diet and their activities contribute to the rate of ethanol elimination from the blood. They are expressed at highest
Jae-Young Cha et al.
Journal of microbiology and biotechnology, 21(8), 791-795 (2011-08-31)
Sea tangle, a kind of brown seaweed, was fermented with Lactobacillus brevis BJ-20. The gamma-aminobutyric acid (GABA) content in fermented sea tangle (FST) was 5.56% (w/w) and GABA in total free amino acid of FST was 49.5%. The effect of
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