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关于此项目
经验公式(希尔记法):
C13H14N2O8
化学文摘社编号:
分子量:
326.26
UNSPSC Code:
12161502
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
8575145
Quality Level
assay
≥97.0% (CHN)
form
lumps
reaction suitability
reagent type: cross-linking reagent
storage temp.
−20°C
SMILES string
O=C(CCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O
InChI
1S/C13H14N2O8/c16-8-4-5-9(17)14(8)22-12(20)2-1-3-13(21)23-15-10(18)6-7-11(15)19/h1-7H2
InChI key
LNQHREYHFRFJAU-UHFFFAOYSA-N
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
Other Notes
作为同双功能交联试剂;例如,用于胰岛素受体的分离
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
S M Waugh et al.
Biochemistry, 28(8), 3448-3455 (1989-04-18)
Radiolabeled insulin was affinity cross-linked to purified insulin receptor with six separate bifunctional N-hydroxysuccinimide esters of different lengths. Results were qualitatively identical for each cross-linker in that insulin was predominantly cross-linked through its B chain to the receptor's alpha subunit.
Jing Xu et al.
Cell discovery, 2, 16008-16008 (2016-07-28)
Mixed lineage leukemia protein-1 (MLL1) has a critical role in human MLL1 rearranged leukemia (MLLr) and is a validated therapeutic target. However, its role in regulating global gene expression in MLLr cells, as well as its interplay with MLL1 fusion
Nikki Minnebo et al.
Nucleic acids research, 41(2), 842-854 (2012-12-18)
The histone methyltransferase EZH2 regulates cell proliferation and differentiation by silencing Polycomb group target genes. NIPP1, a nuclear regulator of serine/threonine protein phosphatase 1 (PP1), has been implicated in the regulation of EZH2 occupancy at target loci, but the underlying
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 392103-500ML | 04061837405297 |
| 392103-1L | 04061831981346 |
| 392103-100ML | 04061831981339 |
| 80424-5MG-F | 04061832979632 |
| 80424-50MG-F | 04061832979625 |
