所有图片(1)
About This Item
经验公式（希尔记法）:
C15H12O4
CAS号:
分子量:
256.25
Beilstein:
359378
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.28
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质量水平
方案
≥97.0% (HPLC)
表单
powder or crystals
杂质
≤7% water
应用
metabolomics
vitamins, nutraceuticals, and natural products
SMILES字符串
Oc1ccc(cc1)[C@@H]2CC(=O)c3ccc(O)cc3O2
InChI
1S/C15H12O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-7,14,16-17H,8H2/t14-/m0/s1
InChI key
FURUXTVZLHCCNA-AWEZNQCLSA-N
一般描述
甘草素是一种黄酮类化合物和雌激素化合物，发现于甘草（甘草根）的根提取物和其他几种植物。
应用
甘草素已：
- 用于研究其在结直肠癌治疗中对肿瘤转移的抑制作用
- 用作柴胡疏肝散(CSS)提取物超高效液相色谱(UPLC)的参比标准品
- 用作一种潜在的抗丙肝病毒(HCV)感染的抗病毒药物
生化/生理作用
甘草素具有抗糖尿病和抗胆汁的特性。它通过抑制活化B细胞核因子卡帕轻链增强子(NF-κB)依赖的诱导性NOS (iNOS)诱导，对Raw246.7细胞产生抗炎活性。甘草素可通过阻挡Hippo/Yes相关蛋白质并转化生长因子-β1 (TGF-β1)/小母抗Dpp (Smad)组分抑制肝纤维化形成。它是一种选择性雌激素受体β调节剂细胞。甘草素通过破坏线粒体膜电位和增加活性氧的产生而诱导SMM-721细胞凋亡。
包装
无底玻璃瓶。内含物装在插入的融合锥内。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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