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Merck
CN

77636

Sigma-Aldrich

酚酞β-D-葡萄糖苷酸

≥98% (TLC)

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别名:
酚酞β-D-葡萄糖醛酸, 酚酞单-β-D-葡糖醛酸, 酚酞葡糖醛酸
经验公式(希尔记法):
C26H22O10
CAS号:
分子量:
494.45
Beilstein:
68526
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.83

生物来源

rabbit urine

检测方案

≥98% (TLC)

形式

powder

杂质

≤0.5% free phenolphthalein
≤6% water

溶解性

H2O: 0.1 g/mL, clear, light yellow

储存温度

−20°C

SMILES字符串

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)C3(OC(=O)c4ccccc34)c5ccc(O)cc5

InChI

1S/C26H22O10/c27-15-9-5-13(6-10-15)26(18-4-2-1-3-17(18)24(33)36-26)14-7-11-16(12-8-14)34-25-21(30)19(28)20(29)22(35-25)23(31)32/h1-12,19-22,25,27-30H,(H,31,32)/t19-,20-,21+,22-,25+,26?/m0/s1

InChI key

FXJYOZKDDSONLX-XADSOVDISA-N

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应用

β-glucuronidase test: suitable as substrate, for liver and bacterial enzymes

其他说明

Characterization of β-glucuronidase from Ampullaria

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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T. Tsukada et al.
Comparative Biochemistry and Physiology, 86B, 565-565 (1987)
Inhibitory effect of bile acids on the activity of human beta-glucuronidase at its optimal pH.
K J Ho et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 167(3), 304-309 (1981-07-01)
Miklós Csala et al.
Biochemical pharmacology, 68(7), 1353-1362 (2004-09-04)
The transport of glucuronides across the endoplasmic reticulum membrane is an important step in the overall process of biotransformation, although the mechanism remains unclear and the participating transporters are unidentified. Using a rapid filtration assay in combination with liquid chromatography-mass
W E Kurtin et al.
Analytical biochemistry, 147(2), 511-516 (1985-06-01)
A method for improving the assay of beta-glucuronidase in hepatic and gallbladder bile is described. The method uses ion-pair extraction with N,N,N-triheptyl-1-heptanaminium bromide to remove pigments and bile acids. Conjugated bilirubin, unconjugated bilirubin, and taurine and glycine conjugates of deoxycholic
Z K Sharaiha et al.
Digestive diseases and sciences, 28(9), 827-832 (1983-09-01)
Phenolphthalein is an odorless, tasteless compound, poorly soluble in water, but readily soluble in alcohol or ether. Although its laxative activity was discovered in 1902, the mechanism of action remains unclear. Phenolphthalein has been found to be an ineffective laxative

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