推荐产品
生物来源
synthetic
质量水平
方案
≥98.0% (NT)
表单
liquid
旋光性
[α]20/D +30±1°, c = 5% in H2O
杂质
≤0.002% heavy metals
≤0.5% 3-aminopropanol
灼烧残渣
≤0.1% (as SO4)
颜色
colorless
折射率
n20/D 1.496-1.500
密度
1.20 g/mL at 20 °C (lit.)
储存温度
2-8°C
SMILES字符串
CC(C)(CO)[C@@H](O)C(=O)NCCCO
InChI
1S/C9H19NO4/c1-9(2,6-12)7(13)8(14)10-4-3-5-11/h7,11-13H,3-6H2,1-2H3,(H,10,14)/t7-/m0/s1
InChI key
SNPLKNRPJHDVJA-ZETCQYMHSA-N
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应用
- 尿囊素、没药醇、D-泛醇和甘草酸二钾的联用减轻了UVB诱导的角化细胞中PGE（2）的合成: 该研究考察了D-泛醇与其它化合物联用对角化细胞中UVB诱导的炎症的保护作用。 研究结果强调了D-泛醇在皮肤护理配方中的作用，旨在减少紫外线引起的损伤和炎症（Tan et al., 2024）。
- D-泛醇对横纹肌溶解症导致的急性肾损伤的保护作用。: 该研究探讨了D-泛醇在减轻横纹肌溶解症引起的急性肾损伤方面的保护作用。研究结果表明，D-泛醇在肾脏保护和恢复方面有潜在的治疗应用价值（Semenovich et al., 2022）。
- α-甘油磷酰胆碱和D-泛酚滴眼液在白内障手术患者中的应用。: 这项临床研究考察了含D-泛醇滴眼液在接受白内障手术的患者中的疗效，证明了其增强术后恢复和眼睛健康的潜力（Martone et al., 2022）。
- 常见化妆品化合物可以减少空气污染引起的皮肤氧化应激和促炎反应。: 该研究重点关注了D-泛醇保护皮肤免受空气污染引起的氧化应激和炎症的作用，强调了其在城市环境化妆品配方中的重要性（Hergesell et al., 2022）。
生化/生理作用
D-泛醇是 D-泛酸的醇类似物和生物前体。这些类似物是辅酶 A 生物合成的前体。D-泛醇和 D-泛酸用于各种皮肤保护产品。D-泛酸可能具有控制角质形成细胞增殖和分化的角色。D-泛醇可用于紫外线照射皮肤保护乳剂的研究，也可作为湿润剂。
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves
X Hui et al.
International journal of cosmetic science, 29(4), 277-282 (2008-05-21)
The in vitro absorption of panthenol into and through the human nail was examined in this study. Panthenol, the alcohol form of pantothenic acid (vitamin B5), is believed to act as a humectant and improve the flexibility and strength of
D Hoeller Obrigkeit et al.
Cutaneous and ocular toxicology, 25(1), 13-22 (2006-05-17)
To investigate the effect of cell growth-stimulating agents on human epidermal keratinocytes, we exposed monolayers of normal human keratinocytes derived from foreskin to different concentrations of the amino acid L-cystine, the member of the vitamin B family D-pantothenat, the phytosterol
Tonio Wiederholt et al.
Experimental dermatology, 18(11), 969-978 (2009-04-29)
Topical application of pantothenate is widely used in clinical practice for wound healing. Previous studies identified a positive effect of pantothenate on migration and proliferation of cultured fibroblasts. However, these studies were mainly descriptive with no molecular data supporting a
Daisaku Kobayashi et al.
Journal of pharmacological sciences, 115(2), 230-234 (2011-01-25)
It has been reported that pantothenic acid (vitamin B5) and panthenol, an alcohol derivative of pantothenic acid, have beneficial moisturizing effects on the skin. However, few studies have investigated the mechanism of action of pantothenic acid on skin tissues. We
W Gehring et al.
Arzneimittel-Forschung, 50(7), 659-663 (2000-08-31)
In a randomized, double-blind, placebo-controlled study the effect of topical dexpanthenol (CAS 81-13-0) formulated in two different lipophilic vehicles on epidermal barrier function in vivo was carried out. Seven days' treatment with dexpanthenol improved stratum corneum hydration and reduced transepidermal
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