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Merck
CN

76200

Sigma-Aldrich

D-泛醇

≥98.0% (NT)

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别名:
(R)-(+)-2,4-二羟基-N-(3-羟基丙基)-3,3-二甲基丁酰胺, 右旋泛酰醇, 右旋泛醇, 维生素原 B
经验公式(希尔记法):
C9H19NO4
CAS号:
分子量:
205.25
Beilstein:
1724947
EC 号:
MDL编号:
UNSPSC代码:
12352104
PubChem化学物质编号:
NACRES:
NA.28

生物来源

synthetic

质量水平

检测方案

≥98.0% (NT)

形式

liquid

旋光性

[α]20/D +30±1°, c = 5% in H2O

杂质

≤0.002% heavy metals
≤0.5% 3-aminopropanol

灼烧残渣

≤0.1% (as SO4)

颜色

colorless

折射率

n20/D 1.496-1.500

密度

1.20 g/mL at 20 °C (lit.)

储存温度

2-8°C

SMILES字符串

CC(C)(CO)[C@@H](O)C(=O)NCCCO

InChI

1S/C9H19NO4/c1-9(2,6-12)7(13)8(14)10-4-3-5-11/h7,11-13H,3-6H2,1-2H3,(H,10,14)/t7-/m0/s1

InChI key

SNPLKNRPJHDVJA-ZETCQYMHSA-N

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应用


  • The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE(2) synthesis by keratinocytes.: This study investigates the protective effects of D-panthenol, combined with other compounds, against UVB-induced inflammation in keratinocytes. The results highlight D-panthenol′s role in skin care formulations aimed at reducing UV-induced damage and inflammation (Tan et al., 2024).

  • Protective Effect of D-Panthenol in Rhabdomyolysis-Induced Acute Kidney Injury.: This research explores the protective properties of D-panthenol in mitigating acute kidney injury caused by rhabdomyolysis. The findings suggest potential therapeutic applications for D-panthenol in renal protection and recovery (Semenovich et al., 2022).

  • Alpha-Glycerylphosphorylcholine and D-Panthenol Eye Drops in Patients Undergoing Cataract Surgery.: This clinical study examines the efficacy of eye drops containing D-panthenol in patients undergoing cataract surgery, demonstrating its potential to enhance postoperative recovery and eye health (Martone et al., 2022).

  • Common Cosmetic Compounds Can Reduce Air Pollution-Induced Oxidative Stress and Pro-Inflammatory Response in the Skin.: This study highlights the role of D-panthenol in protecting the skin against oxidative stress and inflammation caused by air pollution, emphasizing its importance in cosmetic formulations for urban environments (Hergesell et al., 2022).

生化/生理作用

D-泛醇是 D-泛酸的醇类似物和生物前体。这些类似物是辅酶 A 生物合成的前体。D-泛醇和 D-泛酸用于各种皮肤保护产品。D-泛酸可能具有控制角质形成细胞增殖和分化的角色。D-泛醇可用于紫外线照射皮肤保护乳剂的研究,也可作为湿润剂。

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves


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X Hui et al.
International journal of cosmetic science, 29(4), 277-282 (2008-05-21)
The in vitro absorption of panthenol into and through the human nail was examined in this study. Panthenol, the alcohol form of pantothenic acid (vitamin B5), is believed to act as a humectant and improve the flexibility and strength of
M Göbbels et al.
Klinische Monatsblatter fur Augenheilkunde, 209(2-3), 84-88 (1996-08-01)
In this controlled, randomized, double-masked study the effect of dexpanthenol-containing artificial tears (Siccaprotect) on patients with dry eyes was examined. 50 patients applied either dexpanthenol-containing artificial tears (Siccaprotect) or the identical, but free of dexpanthenol, eye drops five times daily
M Sachs et al.
Zeitschrift fur Ernahrungswissenschaft, 29(4), 270-283 (1990-12-01)
The aim of this study was the examination of the metabolism and mechanism of action of D-pantothenyl alcohol in patients with postoperative intestinal atony. Seven metabolically healthy patients were examined on the 4th day following colorectal surgery, before bowel activity
Fritz Ebner et al.
American journal of clinical dermatology, 3(6), 427-433 (2002-07-13)
Pantothenic acid is essential to normal epithelial function. It is a component of coenzyme A, which serves as a cofactor for a variety of enzyme-catalyzed reactions that are important in the metabolism of carbohydrates, fatty acids, proteins, gluconeogenesis, sterols, steroid
C F Zanatta et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(1), 70-75 (2009-09-22)
Considering the belief that natural lipids are safer for topical applications and that carotenoids are able to protect cells against photooxidative damage, we have investigated whether topical creams and lotions, produced with Buriti oil and commercial surfactants, can exert photoprotective

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