75447
2-氧代己二酸 单钠盐
≥95.0% (HPLC)
别名:
α-酮己二酸 单钠盐, 2-己二酸, 2-氧己二酸 单钠盐
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关于此项目
经验公式（希尔记法）:
C6H8O5
化学文摘社编号:
分子量:
160.12
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Application
- 来自中间型高温放线菌用于生产新同型谷氨酸的苯丙氨酸脱氢酶的设计：展示了2-氧代己二酸在酶工程中的应用，增强了用于生产新型化合物的生物催化过程，这对制药和化学工业至关重要（Tariq et al., 2022）。
Biochem/physiol Actions
TCA循环和赖氨酸生物合成之间的重要代谢物。 对于线粒体代谢物转运蛋白具有意义。
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
D G Hine et al.
Biomedical mass spectrometry, 11(7), 332-339 (1984-07-01)
Numerous abnormal metabolites were identified in large amounts in the urine of hypoglycin-treated rats using capillary gas chromatography/mass spectrometry-computer analysis. These metabolites are not detectable in significant amounts in normal rats' urine. Ten of them have not been previously associated
A fatal case of 2-keto-, 2-hydroxy- and 2-aminoadipic aciduria: relation of organic aciduria to phenotype?
C Jakobs et al.
Journal of inherited metabolic disease, 15(2), 279-280 (1992-01-01)
Andrea Schulze-Bergkamen et al.
Pediatric research, 58(5), 873-880 (2005-09-27)
Organic acid (OAD) and fatty acid oxidation disorders (FAOD) are inborn errors of metabolism often presenting with life-threatening metabolic decompensation followed by (irreversible) organ failure, and even death during catabolic state. Most of these diseases are considered as treatable, and
Nikolaus Sonnenschein et al.
BMC systems biology, 6, 41-41 (2012-05-16)
Integrating gene expression profiles and metabolic pathways under different experimental conditions is essential for understanding the coherence of these two layers of cellular organization. The network character of metabolic systems can be instrumental in developing concepts of agreement between expression
D Darmaun et al.
Journal of chromatography, 620(1), 33-38 (1993-10-22)
A method is described for measuring glutamine (GLN) and alpha-ketoglutarate (KG) concentration and specific activity (SA) using high-performance liquid chromatography (HPLC). Plasma GLN and KG are separated on miniature ion-exchange columns. KG is derivatized with O-phenylene diamine, the derivative is
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