75447
2-氧代己二酸 单钠盐
≥95.0% (HPLC)
别名:
α-酮己二酸 单钠盐, 2-己二酸, 2-氧己二酸 单钠盐
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关于此项目
经验公式（希尔记法）:
C6H8O5
化学文摘社编号:
分子量:
160.12
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Assay:
≥95.0% (HPLC), ≥97.0% (T)
Form:
powder
Quality Level
assay
≥95.0% (HPLC), ≥97.0% (T)
form
powder
lipid type
saturated FAs
storage temp.
2-8°C
SMILES string
OC(=O)CCCC(=O)C(O)=O
InChI
1S/C6H8O5/c7-4(6(10)11)2-1-3-5(8)9/h1-3H2,(H,8,9)(H,10,11)
InChI key
FGSBNBBHOZHUBO-UHFFFAOYSA-N
Application
- 来自中间型高温放线菌用于生产新同型谷氨酸的苯丙氨酸脱氢酶的设计：展示了2-氧代己二酸在酶工程中的应用，增强了用于生产新型化合物的生物催化过程，这对制药和化学工业至关重要（Tariq et al., 2022）。
Biochem/physiol Actions
TCA循环和赖氨酸生物合成之间的重要代谢物。 对于线粒体代谢物转运蛋白具有意义。
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
R Lukacin et al.
European journal of biochemistry, 249(3), 748-757 (1997-12-12)
Flavanone 3beta-hydroxylase, involved in the biosynthesis of flavonoids, catechins, and anthocyanidins, is a non-heme iron enzyme, dependent on Fe2+, molecular oxygen, 2-oxoglutarate, and ascorbate, the typical cofactors of the class of 2-oxoglutarate-dependent dioxygenases. Sequence alignment analysis of various 2-oxoglutarate-dependent dioxygenases
Iwona Gabriel et al.
FEMS yeast research, 13(2), 143-155 (2012-10-31)
The LYS12 gene from Candida albicans, coding for homoisocitrate dehydrogenase was cloned and expressed as a His-tagged protein in Escherichia coli. The purified gene product catalyzes the Mg(2+)- and K(+)-dependent oxidative decarboxylation of homoisocitrate to α-ketoadipate. The recombinant enzyme demonstrates
S A Osmani et al.
European journal of biochemistry, 147(1), 119-128 (1985-02-15)
Cell-free extracts of Rhizopus arrhizus contain exclusively cytosolic pyruvate carboxylase and NAD-glutamate dehydrogenase, a single mitochondrial isoenzyme of NADP-isocitrate dehydrogenase, and both mitochondrial and cytosolic isoenzymes of NADP-malate dehydrogenase (decarboxylating). Other enzymes examined have sub-cellular localisations similar to those characteristic
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 75447-100MG | 04061832907970 |
| 75447-500MG | 04061832907987 |