检测方案
≥95.0% (HPLC)
形式
liquid
储存温度
−20°C
SMILES字符串
O=P(OC)(CCCCCC)OC1=CC=C([N+]([O-])=O)C=C1
InChI
1S/C13H20NO5P/c1-3-4-5-6-11-20(17,18-2)19-13-9-7-12(8-10-13)14(15)16/h7-10H,3-6,11H2,1-2H3
InChI key
RMJQAOXPKANPMM-UHFFFAOYSA-N
应用
This lipase suicide inhibitor can be utilized to determine lipase and hydrolase activity, even in complex protein mixtures. The molar amount of enzyme can be determined by active site titration experiments. The inhibitor is soluble in both DMF and DMSO. Active site titrations should be performed in a pH range from 7-8 considering that higher pH values can lead to appreciable spontaneous hydrolysis. It is recommended to perform corresponding negative controls (buffer only).
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Racemase activity of B. cepacia lipase leads to dual-function asymmetric dynamic kinetic resolution of α-aminonitriles.
Pornrapee Vongvilai et al.
Angewandte Chemie (International ed. in English), 50(29), 6592-6595 (2011-06-03)
G Zandonella et al.
European journal of biochemistry, 262(1), 63-69 (1999-05-07)
Fluorescent triacylglycerol analogs were synthesized as covalent inhibitors of lipase activity. The respective 1(3), 2-O-dialkylglycero-3(1)-alkyl-phosphonic acid p-nitrophenyl esters contain a fluorescent pyrenealkyl chain and a long-chain alkyl residue bound to the sn-2 and sn-1(3) positions of glycerol, respectively. The phosphonic
Nobuhiko Tokuriki et al.
Nature communications, 3, 1257-1257 (2012-12-06)
Optimization processes, such as evolution, are constrained by diminishing returns-the closer the optimum, the smaller the benefit per mutation, and by tradeoffs-improvement of one property at the cost of others. However, the magnitude and molecular basis of these parameters, and
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