73677
4-硝基苯基 β-D-葡糖苷酸
β-glucuronidase substrate, chromogenic, ≥99.0% (TLC), powder or crystals, suitable as substrate for β-glucuronidase test
别名:
4-硝基苯基-β-D-吡喃葡萄糖醛酸, PNPG
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所有图片(1)
About This Item
经验公式（希尔记法）:
C12H13NO9
CAS号:
分子量:
315.23
Beilstein:
1438576
EC 号:
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.32
product name
4-硝基苯基 β-D-葡糖苷酸, ≥99.0% (TLC)
质量水平
检测方案
≥99.0% (TLC)
形式
powder or crystals
旋光性
[α]20/D −102±3°, c = 1% in ethanol
杂质
≤0.05% free 4-nitrophenol
≤7% water
溶解性
H2O: 0.1 g/mL, clear, faintly yellow
适用性
suitable as substrate for β-glucuronidase test
储存温度
−20°C
SMILES字符串
O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)[N+]([O-])=O
InChI
1S/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-3-1-5(2-4-6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/t7-,8-,9+,10-,12+/m0/s1
InChI key
QSUILVWOWLUOEU-GOVZDWNOSA-N
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应用
4-硝基苯基β-D-葡萄糖醛酸苷用于测定尿液样本中β-葡萄糖醛酸苷酶的活性，盲肠内容物消化物细菌和牛肝中β-葡萄糖醛酸苷酶的活性。 也用来研究苦味叶下珠提取物对β-葡萄糖醛酸苷酶的抑制作用。
底物
用于 β-葡萄糖醛酸酶（GUS）基因检测的显色底物。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Effect of dietary honey on intestinal microflora and toxicity of mycotoxins in mice
El-Arab AME, et al.
BMC Complementary and Alternative Medicine, 6(1), 6-6 (2006)
Effect of tobacco smoking on albumin concentration and beta-glucuronidase activity in urine of smelters
Bizonn A, et al.
Przegla?d Lekarski, 71(11), 581-584 (2014)
Synthesis of Glycaro-1, 5-lactams and Tetrahydrotetrazolopyridine-5-carboxylates: Inhibitors of beta-D-Glucuronidase and alpha-L-Iduronidase
Pabba J, et al.
Helvetica Chimica Acta, 89(4), 635-666 (2006)
E E Guibert et al.
Experientia, 39(5), 527-528 (1983-05-15)
The effect of spironolactone (SP) on p-nitrophenol (PNP) glucuronidation was studied in isolated rat hepatocytes with appropriate viability conditions. A significant increase of protein concentration and PNP glucuronidation was found in the hepatocytes from SP-treated rats. Increased enzyme activity apparently
C Y Ng et al.
The Journal of pharmacology and experimental therapeutics, 295(2), 830-835 (2000-10-25)
Congestive heart failure has been shown to affect oxidative drug metabolism, however, there has been little study of its effects on drug conjugation. Using the isolated perfused livers from rats with right ventricular failure (RVF) due to pulmonary artery constriction
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