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Merck
CN

72987

2-脱氧-2-[(7-硝基-2,1,3-苯并恶二唑-4-基)氨基]-D-葡萄糖

≥97% (HPLC)

别名:

2-NBDG, 2-[N-(7-硝基苯-2-氧杂-1,3-二唑-4-基)氨基]-2-脱氧D-葡萄糖

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关于此项目

经验公式(希尔记法):
C12H14N4O8
化学文摘社编号:
分子量:
342.26
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
7603370
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InChI

1S/C12H14N4O8/c17-3-6(11(20)12(21)8(19)4-18)13-5-1-2-7(16(22)23)10-9(5)14-24-15-10/h1-3,6,8,11-13,18-21H,4H2/t6-,8+,11+,12+/m0/s1

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](Nc1ccc([N+]([O-])=O)c2nonc12)C=O

InChI key

QUTFFEUUGHUPQC-ILWYWAAHSA-N

biological source

synthetic

assay

≥97% (HPLC)

form

powder

fluorescence

λex 494 nm; λem 551 nm in DMSO

application(s)

cell analysis

storage temp.

−20°C

Quality Level

General description

2-脱氧-2-[(7-硝基-2,1,3-苯并恶二唑-4-基)氨基]-D-葡萄糖,也称2-NBDG,是发射荧光的D葡萄糖类似物。产生的荧光活性通过流式细胞仪检测。2-NBDG与测试样品一起温育并被摄取,然后进行测定。

Application

2-脱氧-2-[(7-硝基-2,1,3-苯并恶二唑-4-基)氨基]-D-葡萄糖可用作直接葡萄糖摄取测定的荧光指示剂。2-NBDG 可用作研究肿瘤细胞的荧光脱氧葡萄糖类似物。 在癫痫活动实验的体内成像中,2-NBDG可用作荧光脱氧葡萄糖类似物。

Packaging

无底玻璃瓶。内含物装在插入的融合锥内。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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