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Merck
CN

72779

Sigma-Aldrich

三氯生

97.0-103.0% (active substance, GC)

别名:

三氯苯氧氯酚, 5-氯-2-(2,4-二氯苯氧基)苯酚, 氯苯酚

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About This Item

经验公式(希尔记法):
C12H7Cl3O2
CAS号:
分子量:
289.54
Beilstein:
2057142
EC 号:
MDL编号:
UNSPSC代码:
12352132
PubChem化学物质编号:
NACRES:
NA.85

生物来源

synthetic

质量水平

方案

97.0-103.0% (active substance, GC)

表单

powder or crystals

杂质

≤0.1% Water (Karl Fischer)

颜色

white

mp

55-59 °C

溶解性

1 M NaOH: 5% at 25 °C, faintly turbid to clear (colorless solution)

抗生素抗菌谱

fungi

作用机制

enzyme | inhibits

SMILES字符串

Oc1cc(Cl)ccc1Oc2ccc(Cl)cc2Cl

InChI

1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H

InChI key

XEFQLINVKFYRCS-UHFFFAOYSA-N

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一般描述

化学结构式:二苯醚衍生物

应用

一种可能污染动物性食品的人类病原体—耶尔森氏菌的头孢菌素-伊桑-新生物素选择培养基的组成部分。

生化/生理作用

它是细菌和疟原虫II型脂肪酸合成酶(FAS-II)的烯酰ACP(酰基载体蛋白)还原酶组分的抑制剂。 它还能抑制哺乳动物脂肪酸合成酶(FASN),可能具有抗癌活性。

其他说明

将容器紧紧地封闭在干燥通风良好的地方。保存在干燥的地方。

象形图

Exclamation markEnvironment

警示用语:

Warning

危险声明

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is Product 72779, Irgasan, soluble in?

    Per the chemicals encyclopedia published by the Royal Society of Chemistry, 12th edition, Entry# 9790, Irgasan is not soluble in water, but it is readily soluble in alkaline solutions and many organic solvents.

  4. What are other names besides Irgasan that Product 72779 may be referred to?

    Irgasan may also be referred to as Triclosan and 5-Chloro-2-(2,4-dichlorophenoxy)phenol.

  5. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  6. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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Recent publications have raised concerns of reduced susceptibilities of clinical bacterial isolates towards biocides. This study presents a comparative investigation of the susceptibility of livestock-associated Methicillin-resistant Staphylococcus aureus (LA-MRSA), hospital-acquired MRSA (HA-MRSA) and community-aquired MRSA (CA-MRSA) to the commonly used
Cale T Anger et al.
Environmental science & technology, 47(4), 1833-1843 (2013-01-17)
When discharged into surface waters via wastewater effluents, triclosan, the antimicrobial agent in handsoaps, and chlorinated triclosan derivatives (CTDs, formed during disinfection with chlorine) react photochemically to form polychlorinated dibenzo-p-dioxins. To evaluate the historical exposure of waters to these compounds
Joseph V Rodricks et al.
Critical reviews in toxicology, 40(5), 422-484 (2010-04-10)
Triclosan (2,4,4'-trichloro-2'-hydroxy-diphenyl ether) is an antibacterial compound that has been used in consumer products for about 40 years. The tolerability and safety of triclosan has been evaluated in human volunteers with little indication of toxicity or sensitization. Although information in
Wai Keat Chang et al.
Annals of surgery, 255(5), 854-859 (2012-04-04)
To determine the efficacy and safety of triclosan-impregnated sutures. Surgical-site infections (SSIs) produce considerable morbidity and increase health care costs. A potential strategy to decrease the rates of SSIs may be the use of triclosan-impregnated sutures. These have been endorsed
Z X Wang et al.
The British journal of surgery, 100(4), 465-473 (2013-01-23)
Surgical-site infections (SSIs) increase morbidity and mortality in surgical patients and represent an economic burden to healthcare systems. Experiments have shown that triclosan-coated sutures (TCS) are beneficial in the prevention of SSI, although the results from individual randomized controlled trials

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