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Merck
CN

72335

Sigma-Aldrich

9-(2,2-二氰乙烯基)久洛啶

BioReagent, suitable for fluorescence, ≥97.0% (HPLC)

别名:

9-久洛啶基亚甲基丙二腈, DCVJ

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About This Item

经验公式(希尔记法):
C16H15N3
CAS号:
分子量:
249.31
Beilstein:
413882
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.32

产品线

BioReagent

质量水平

方案

≥97.0% (HPLC)

表单

crystals

溶解性

DMSO: soluble
chloroform: soluble

荧光

λex 433 nm; λem 500 nm in 50 mM Tris pH 8.0; 40% glycerol

适用性

suitable for fluorescence

SMILES字符串

N#C\C(=C/c1cc2CCCN3CCCc(c1)c23)C#N

InChI

1S/C16H15N3/c17-10-13(11-18)7-12-8-14-3-1-5-19-6-2-4-15(9-12)16(14)19/h7-9H,1-6H2

InChI key

LROAUBRDKLVBCP-UHFFFAOYSA-N

包装

无底玻璃瓶。内容物在插入式融锥内。

其他说明

作为荧光探针,用于结合蛋白质等,通过减少自由旋转来增加量子产率;吸收波长在~450nm处,发射波长在480-505nm处(溶剂dep.)

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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M A Haidekker et al.
American journal of physiology. Heart and circulatory physiology, 278(4), H1401-H1406 (2000-04-06)
Fluid shear stress (FSS) has been shown to be an ubiquitous stimulator of mammalian cell metabolism. Although many of the intracellular signal transduction pathways have been characterized, the primary mechanoreceptor for FSS remains unknown. One hypothesis is that the cytoplasmic
A Bhattacharyya et al.
Indian journal of biochemistry & biophysics, 32(6), 442-446 (1995-12-01)
Di(cyano vinyl)julolidine (DCVJ) is a fluorescent probe which has been used to monitor the local mobility of its binding sites on proteins. It shows a concentration dependence of its emission spectrum in water. At higher DCVJ concentrations, a longer wavelength
Andrea Hawe et al.
Pharmaceutical research, 27(2), 314-326 (2009-12-31)
The aim was to evaluate fluorescent molecular rotors (DCVJ and CCVJ), which are mainly sensitive to viscosity, for the characterization of polysorbate-containing IgG formulations and compare them to the polarity-sensitive dyes ANS, Bis-ANS and Nile Red. IgG formulations with polysorbate
A Bhattacharya et al.
Protein science : a publication of the Protein Society, 5(10), 2029-2036 (1996-10-01)
9-(Dicyanovinyl) julolidine (DCVJ) is a fluorescent probe, which binds to a unique site on the tubulin dimer and exhibits different properties that are dependent upon its oligomeric state (Kung & Reed, 1989). DCVJ binds to tubulin, the tubulin-colchicine complex, and
T Iio et al.
Journal of biochemistry, 109(4), 499-502 (1991-04-01)
A molecular rotor, 9-(dicyanovinyl)julolidine (DCVJ), is a fluorescent dye whose intramolecular rotation determines its fluorescence yield [Kung, C.E. & Reed, J.K. (1989) Biochemistry 28, 6678-6686]. DCVJ binds to bovine brain calmodulin and emits strong fluorescence. In fluorescence titration experiments, the

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