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Merck
CN

71162

Sigma-Aldrich

柚皮苷

≥95% (HPLC)

别名:

4‘;5,7-三羟基黄酮 7-鼠李糖苷, 柚皮素 7-新橙皮苷, 柚皮素-7-鼠李糖苷, 柚皮苷

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About This Item

经验公式(希尔记法):
C27H32O14
CAS号:
分子量:
580.53
Beilstein:
102012
EC 号:
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.47

质量水平

方案

≥95% (HPLC)

表单

powder

旋光性

[α]20/D −80±10°, c = 1% in ethanol

mp

83  °C ((181 °F ))

溶解性

ethanol: o.1 g/10 mL, clear to hazy, colorless to light greenish-yellow

SMILES字符串

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)CC(Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16?,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1

InChI key

DFPMSGMNTNDNHN-JJLSSNRUSA-N

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应用

柚皮苷用于:
  • 作为苦味剂,比较 果蝇 幼虫和成虫的行为反应(2)
  • 研究其抗炎特性,确定其对髓核(NP)细胞的作用(3)
  • 确定其对骨代谢的影响,如成骨分化、抑制破骨细胞形成(4)。

生化/生理作用

柚皮苷可以与信号分子相互作用,调节信号通路。具有抗炎和抗癌活性。它还对氧化应激、骨骼再生、遗传损伤、代谢综合征和中枢神经系统(CNS)疾病具有药理作用。
柚皮苷是葡萄柚和其他柑橘类水果中的黄酮类化合物,可强效抑制肠道有机阴离子转运多肽 1A2 (OATP1A2)。因此,葡萄柚汁可降低同时服用的许多药物的生物利用度。

其他说明

为了全面了解我们针对客户研究提供的各种二糖产品,建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Marcelo Silva et al.
Industrial & engineering chemistry research, 57(28), 9210-9221 (2018-10-03)
Liquid-liquid extraction (LLE) can be an effective strategy for the purification of polyphenols from a fermentation broth. However, solvents need to be chosen to ensure high extraction capacity and selectivity. For that purpose, a systematic study is here presented, where
Therapeutic potential of naringin: an overview
Chen R, et al.
Pharmaceutical biology, 54(12), 3203-3210 (2016)
Luís F Mendes et al.
Scientific reports, 9(1), 14906-14906 (2019-10-19)
The ability of flavonoids to attenuate macrophage pro-inflammatory activity and to promote macrophage-mediated resolution of inflammation is still poorly understood at the biochemical level. In this study, we have employed NMR metabolomics to assess how therapeutically promising flavonoids (quercetin, naringenin
Susana Ferreyra et al.
Food chemistry, 338, 128030-128030 (2020-09-16)
A liquid chromatography method coupling diode-array and fluorescence detectors (DAD and FLD, respectively) has been developed for the simultaneous quantification of 32 phenolic compounds (PCs) in winemaking products. With the combination of both detectors it was possible to determine phenolic
Jiukai Zhang et al.
Food chemistry, 135(3), 1471-1478 (2012-09-08)
Huyou (Citrus changshanensis) is rich in naringin and neohesperidin, which are natural flavanone glycosides with a range of biological activities. Among the different fruit parts, i.e. flavedo, albedo, segment membrane (SM), and juice sacs (JS), albedo showed the highest contents

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