70215
2,3-萘二甲醛
suitable for fluorescence
别名:
NDA
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关于此项目
线性分子式:
C10H6(CHO)2
化学文摘社编号:
分子量:
184.19
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2207267
Form:
crystals
产品名称
2,3-萘二甲醛, suitable for fluorescence
InChI key
ZIPLKLQPLOWLTM-UHFFFAOYSA-N
SMILES string
[H]C(=O)c1cc2ccccc2cc1C([H])=O
InChI
1S/C12H8O2/c13-7-11-5-9-3-1-2-4-10(9)6-12(11)8-14/h1-8H
form
crystals
impurities
≤2% mono- and dicarboxylic acid (1H-NMR)
mp
131-133 °C (lit.)
132-135 °C
fluorescence
λex 420 nm; λem ~480 nm in 0.1 M borate pH 9.3 (after derivatization with glycine [~90 μM glycine, ~20 μM N-])
suitability
suitable for fluorescence
storage temp.
2-8°C
Quality Level
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Application
2,3-萘二甲醛用作荧光标记剂，用于定量人免疫球蛋白制剂中的组胺。 NAD 被用作谷胱甘肽的衍生剂，以定量蛋白质谷胱甘肽化。它是一种适合用于开发基于荧光的 γ-谷氨酰环转移酶微量滴定板测定的试剂。
Features and Benefits
与邻苯二甲醛（OPA）相比，基于 NDA 的荧光分析具有以下优势：
- 高反应速率。
- 高荧光量子产率。
- 没有罕见的激发波长。
- 无副反应。
General description
2,3-萘二甲醛，又称 NDA，是一种新型的荧光衍生剂。NDA 的最大荧光激发在 424nm 范围内，最大发射在 484nm 处。
2,3-萘二甲醛是伯胺、氨基酸和小肽的荧光衍生剂。氨基化合物和 NDA 之间的反应产生高度荧光和稳定的衍生物化合物。
2,3-萘二甲醛是伯胺、氨基酸和小肽的荧光衍生剂。氨基化合物和 NDA 之间的反应产生高度荧光和稳定的衍生物化合物。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Richard C Kevin et al.
Forensic toxicology, 37(1), 17-26 (2019-02-02)
The use of novel synthetic cannabinoids as intoxicants continues in spite of associated health risks. These compounds are typically smoked or vaporized, but many synthetic cannabinoids contain thermally labile chemical moieties. This study investigated the thermal stability six carboxamide-type synthetic
T. Ueda et al.
Analytical Chemistry, 63, 2979-2979 (1991)
Stéphanie Marchand et al.
Analytica chimica acta, 660(1-2), 158-163 (2010-01-28)
A simple and automated high performance liquid chromatography (HPLC) method for the separation and quantitative determination of gamma-glutamylcysteine and reduced glutathione (GSH) in wines is reported. This technique involves the use of a pre-column derivatization with 2,3-naphthalenedialdehyde (NDA), an isocratic
Yu-Yen Kao et al.
Journal of chromatography. A, 1217(4), 582-587 (2009-12-17)
We describe simultaneous analysis of naphthalene-2,3-dicarboxaldehyde (NDA)-amino acid and NDA-biogenic amine derivatives by CE in conjunction with light-emitting diode-induced fluorescence detection using poly(ethylene oxide) (PEO) solutions containing sodium dodecyl sulfate (SDS). After sample injection, via EOF 0.1% PEO prepared in
O Yassine et al.
Analytica chimica acta, 609(2), 215-222 (2008-02-12)
In this work, we developed a PDMS electrophoresis device able to carry out on-chip derivatization and quantification of amino acids (AAs) using naphthalene-2,3-dicarboxaldehyde (NDA) as a fluorogenic agent. A chemical modification of the PDMS surface was found compulsory to achieve
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