68783
甘草查尔酮A
≥96.0% (HPLC)
别名:
(E)-3- [5-（1,1-二甲基-2-丙烯基）-4-羟基-2-甲氧基苯基]-1-（4-羟基苯基）-2-丙烯-1-酮, 4′1,4-二羟基-3-α,α-二甲基烯丙基-6-甲氧基查尔酮
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关于此项目
经验公式（希尔记法）:
C21H22O4
化学文摘社编号:
分子量:
338.40
UNSPSC Code:
41116107
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4534154
General description
Licochalcone A 是一种强效膜活性剂，可将正常红细胞转化为棘形红细胞。一种具有显著抗肿瘤活性的新型黄酮类化合物。
Biochem/physiol Actions
抑制芽孢形成细菌 枯草芽孢杆菌 和其他食品污染微生物的营养生长。
Packaging
无底玻璃瓶。内含物装在插入的融合锥内。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Xiu-ying Xiao et al.
Cancer letters, 302(1), 69-75 (2011-01-11)
The aim of this study was to determine the anticancer effects of seven licorice compounds in MKN-28, AGS, and MKN-45 gastric cancer cells and human gastric epithelium immortalized cells. We also explored the mechanism of action of licochalcone A (LCA)
Ryo-Ichi Tsukiyama et al.
Antimicrobial agents and chemotherapy, 46(5), 1226-1230 (2002-04-18)
Licochalcone A was isolated from the roots of licorice, Glycyrrhiza inflata, which has various uses in the food and pharmaceutical industries; isolation was followed by extraction with ethanol and column chromatography with silica gel. In this study, the activities of
M Udompataikul et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 25(6), 660-665 (2010-09-16)
Although moisturizer usage has been considered a mainstay of treatment for atopic dermatitis (AD) patients, few clinical studies have been investigated. Recently, moisturizers containing non-steroidal anti-inflammatory agents, such as licochalcone A (LA) and vitamin B(12) are of emerging interest. To
Jin-Kyung Kim et al.
Journal of molecular medicine (Berlin, Germany), 88(8), 829-838 (2010-04-13)
Licochalcone A (LicA), a major phenolic constituent of licorice, has antiproliferative and anti-inflammatory properties in human and murine cell lines. We previously showed that LicA down-regulates the expression of cyclooxygenase (COX)-2 and inducible nitric oxide synthase (iNOS) via the modulation
Xiao Chu et al.
Journal of agricultural and food chemistry, 60(15), 3947-3954 (2012-03-10)
Licochalcone A (Lico A), a flavonoid found in licorice root (Glycyrrhiza glabra), is known for its antimicrobial activity and its reported ability to inhibit cancer cell proliferation. In the present study, we found that Lico A exerted potent anti-inflammatory effects
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