InChI
1S/C10H17NO6/c1-10(2,4-11)17-9-8(15)7(14)6(13)5(3-12)16-9/h5-9,12-15H,3H2,1-2H3/t5-,6-,7+,8-,9+/m1/s1
SMILES string
CC(C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C#N
InChI key
QLTCHMYAEJEXBT-ZEBDFXRSSA-N
biological source
synthetic
assay
≥97% (HPLC)
form
solid
optical activity
[α]/D -26.5±2.0°, c = 1 in H2O
technique(s)
HPLC: suitable
color
white to off-white
storage temp.
2-8°C
Quality Level
signalword
Warning
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Kirsten Jørgensen et al.
Plant physiology, 155(1), 282-292 (2010-11-04)
Cassava (Manihot esculenta) is a eudicotyledonous plant that produces the valine- and isoleucine-derived cyanogenic glucosides linamarin and lotaustralin with the corresponding oximes and cyanohydrins as key intermediates. CYP79 enzymes catalyzing amino acid-to-oxime conversion in cyanogenic glucoside biosynthesis are known from
Vega García-Escudero et al.
Autophagy, 4(7), 923-925 (2008-08-22)
The understanding of the mechanisms of cell-death execution and the role that they play in different diseases opens new therapeutic strategies. Currently, increasing evidence indicates that autophagy is a frequent cell-death mechanism, so the question arises: Could autophagy stimulation be
Karin Forslund et al.
Plant physiology, 135(1), 71-84 (2004-05-04)
Lotus japonicus was shown to contain the two nitrile glucosides rhodiocyanoside A and rhodiocyanoside D as well as the cyanogenic glucosides linamarin and lotaustralin. The content of cyanogenic and nitrile glucosides in L. japonicus depends on plant developmental stage and
Bala Nambisan
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(3), 690-693 (2010-11-16)
Toxicity of cassava arises due to the presence of the cyanoglucosides linamarin and lotaustralin which are hydrolysed by endogenous enzyme linamarase to acetonecyanohydrin (ACN) and cyanide (CN) which are toxic. Major research efforts to eliminate/reduce cyanoglucosides have focused on (i)
Christopher Avwoghokoghene Idibie et al.
Bioprocess and biosystems engineering, 30(4), 261-269 (2007-06-15)
Cassava (Manihot esculenta Crantz) is a known source of linamarin, but difficulties associated with its isolation have prevented it from being exploited as a major source. A batch adsorption process using activated carbon proved successful in its isolation, with ultrafiltration
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