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Merck
CN

65969

Sigma-Aldrich

4-O-咖啡酰奎宁酸

≥98.0%

别名:

4-O-(3,4-二羟基肉桂酰)- D -奎宁酸, 隐绿原酸

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About This Item

经验公式(希尔记法):
C16H18O9
CAS号:
分子量:
354.31
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.28

质量水平

检测方案

≥98.0%

形式

powder or crystals

旋光性

[α]/D -76.0±5.0°, c = 0.5 in H2O

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

2-8°C

SMILES字符串

O[C@@H]1C[C@](O)(C[C@@H](O)[C@@H]1OC(=O)\C=C\c2ccc(O)c(O)c2)C(O)=O

InChI

1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(21)25-14-11(19)6-16(24,15(22)23)7-12(14)20/h1-5,11-12,14,17-20,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14-,16+/m1/s1

InChI key

GYFFKZTYYAFCTR-JUHZACGLSA-N

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一般描述

4-咖啡酰奎宁酸(4-CQA)是咖啡酸(CA)的衍生物。
它是咖啡酸和奎尼酸的酯。

应用

4-O-咖啡酰奎宁酸已用作高效液相色谱-二极管阵列检测器 (HPLC-DAD)法定量分析的参考化合物。

生化/生理作用

4-O-咖啡酰奎宁酸(4-CQA)是桑叶提取物中主要的活性抗氧化标记物。它是一种抑制铁下垂的药物,因此被认为是一种有效的抗糖尿病药物。4-CQA在核因子(红细胞衍生2)-样2 (Nrf2)通路上调中发挥重要作用。

包装

无底玻璃瓶。内容物在插入的熔锥内。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Gary R Takeoka et al.
Journal of agricultural and food chemistry, 51(2), 496-501 (2003-01-09)
Almond hulls (Nonpareil variety) were extracted with methanol and analyzed by reversed phase HPLC with diode array detection. The extract contained 5-O-caffeoylquinic acid (chlorogenic acid), 4-O-caffeoylquinic acid (cryptochlorogenic acid), and 3-O-caffeoylquinic acid (neochlorogenic acid) in the ratio 79.5:14.8:5.7. The chlorogenic
Bioactive Phenolics of the Genus Artemisia (Asteraceae): HPLC-DAD-ESI-TQ-MS/MS Profile of the Siberian Species and Their Inhibitory Potential Against alpha-Amylase and alpha-Glucosidase
Olennikov D N, et al.
Frontiers in Pharmacology, 9 (2018)
Caffeic acid derivatives from Bupleurum chinense
Haghi G, et al.
Research in Pharmaceutical Sciences, 9(5), 323-323 (2014)
Yi Zhou
Diabetes, metabolic syndrome and obesity : targets and therapy, 13, 1921-1931 (2020-07-02)
Mulberry leaf extract has exerted better antidiabetic activities, while the effects of major active components in mulberry leaf extract are still unclear. Cryptochlorogenic acid (CCA) as the major active component in mulberry leaf extracts was investigated herein. Rats were treated
Jerome G Ganzon et al.
Journal of food and drug analysis, 26(3), 985-993 (2018-07-07)
Mulberry (Morus alba L.) leaves are widely used as herbal tea to prevent heat stroke. Potential chemical markers of the antioxidant properties and its correlation with harvesting times and leaf location were explored in this study. A 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging

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