64951
7-甲氧基香豆素
suitable for fluorescence, ≥98.0% (TLC)
别名:
Methyl umbelliferyl ether, 赫尼亚林
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关于此项目
经验公式（希尔记法）:
C10H8O3
化学文摘社编号:
分子量:
176.17
UNSPSC Code:
85151701
NACRES:
NA.32
PubChem Substance ID:
EC Number:
208-513-3
Beilstein/REAXYS Number:
141728
MDL number:
InChI key
LIIALPBMIOVAHH-UHFFFAOYSA-N
InChI
1S/C10H8O3/c1-12-8-4-2-7-3-5-10(11)13-9(7)6-8/h2-6H,1H3
SMILES string
COc1ccc2C=CC(=O)Oc2c1
assay
≥98.0% (TLC)
form
solid
mp
117-121 °C (lit.)
solubility
DMF: soluble, acetonitrile: soluble, alcohols: soluble, chloroform: soluble
fluorescence
λex 350 nm; λem 385 nm (Reaction product), λex 350 nm; λem 385 nm in chloroform
suitability
suitable for fluorescence
Quality Level
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Application
7-Methoxycoumarin (Herniarin) is used to study antioxidant and hepatoprotective properties and its activity as an allergen. 7-Methoxycoumarin may be used as a reference material in the purification, separation and analysis of coumarin compounds.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
M Warren et al.
Xenobiotica; the fate of foreign compounds in biological systems, 18(8), 973-981 (1988-08-01)
1. The activities of 7-methoxycoumarin (7-MCOD), 7-ethoxycoumarin (7-ECOD) and 7-propoxycoumarin (7-PCOD) O-dealkylases decreased by 75-90% during culture of rat hepatocytes for 72 h. 2. The addition of dexamethasone (D) produced a stabilization or modest enhancement of 7-ECOD and 7-PCOD activities
Chao-Mei Ma et al.
Phytochemical analysis : PCA, 18(1), 42-49 (2007-01-31)
A simple HPLC-PAD-MS method was established to quantitatively analyse two spiroether isomers (cis-en-yn-dicycloether and trans-en-yn-dicycloether) and the main coumarin, herniarin, in chamomile herbs, simultaneously. By using this method, the contents of these three compounds in the flowers of two chamomile
P Paterson et al.
Xenobiotica; the fate of foreign compounds in biological systems, 14(11), 849-859 (1984-11-01)
Pretreatment of rats with phenobarbitone increased hepatic microsomal 7-methoxy-and 7-ethoxy-coumarin O-dealkylase activities. Pretreatment with beta-naphthoflavone increased only the 7-ethoxycoumarin O-dealkylase activity. The addition of metyrapone in vitro inhibited the O-dealkylations to different extents. Similar results were obtained with diphenyloxazole and
Adriana Eliasová et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 59(7-8), 543-548 (2005-04-09)
The responses of young plants of diploid and tetraploid Matricaria chamomilla cultivars to abiotic stress were studied. The course of quantitative changes of main leaf secondary metabolites was evaluated within an interval from 6 h before to 54 h after
M Abu Mraheil et al.
Die Pharmazie, 68(7), 541-548 (2013-08-09)
Due to the increasing prevalence of antibiotic resistance and the yet low output of the genomics-based drug discovery approach novel strategies are urgently needed to detect new antibiotics. One such strategy uses known ubiquitous targets like DNA topoisomerases. However, to
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