64382
DL -甲硫氨酸甲磺酰氯
≥97.0% (AT)
别名:
MMS, 甲基蛋氨酸氯化磺铵, 维生素U, （3-氨基-3-羧丙基）二甲基磺酰氯
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关于此项目
经验公式（希尔记法）:
C6H14ClNO2S
化学文摘社编号:
分子量:
199.70
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
EC Number:
222-484-4
Beilstein/REAXYS Number:
4163617
MDL number:
InChI key
MYGVPKMVGSXPCQ-UHFFFAOYSA-N
InChI
1S/C6H13NO2S.ClH/c1-10(2)4-3-5(7)6(8)9;/h5H,3-4,7H2,1-2H3;1H
SMILES string
[Cl-].C[S+](C)CCC(N)C(O)=O
biological source
synthetic
assay
≥97.0% (AT)
form
powder
impurities
≤0.002% heavy metals
ign. residue
≤0.1%
loss
≤3% loss on drying
color
colorless to white
pH
4.0-5.5
mp
139-140 °C
solubility
H2O: 100 mg/mL, clear, colorless
Biochem/physiol Actions
DL-蛋氨酸甲磺 (DL-MMSC) 是一种外消旋混合物，用于研究其保护胃溃疡的机制。DL-MMSC 也可用作蛋氨酸类似物。
S-蛋氨酸甲基 (SMMS) 氯化物是某些植物蛋氨酸代谢的衍生物。SMMS可以过促进皮肤成纤维细胞迁移和生长能力，对胃肠道溃疡具有有效的治疗作用。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
A S Salim
Journal of pharmaceutical sciences, 81(1), 70-73 (1992-01-01)
One milliliter of 1, 2, or 5% DL-cysteine (cysteine) or DL-methionine methylsulfonium chloride (MMSC) was instilled into the rat stomach 1, 24, and 48 h after giving ethanol (1 mL of 40% solution) by gavage. One hour following the administration
A S Salim
Journal of pharmaceutical sciences, 81(7), 698-700 (1992-07-01)
Reserpine (intraperitoneal, 5 mg/kg every day for 5 days) produced chronic ulceration of the rat stomach 2 weeks postdose. Gavage with 1% DL-cysteine or DL-methionine-S-methylsulfonium chloride at 1 mL/day for 2 weeks and 5 days protected against ulceration in 30%
Dharmendra Kumar et al.
Bioresource technology, 96(3), 287-294 (2004-10-12)
The production of methionine by submerged fermentation using a mutant strain of Corynebacterium lilium was studied to determine suitable conditions for obtaining high productivity. The mutant strain resistant to the methionine analogues ethionine, norleucine, methionine sulfoxide and methionine methylsulfonium chloride
A S Salim
Pharmacology, 46(5), 281-288 (1993-05-01)
This prospective randomized double-blind controlled study investigated whether sulphydryl-containing agents protect against the recurrence of duodenal ulceration. To this end, DL-cysteine (200 mg 4 times daily) and DL-methionine-methyl sulphonium chloride (MMSC, 500 mg 4 times daily) were administered orally. Three
Kinuyo Matsumoto et al.
Metallomics : integrated biometal science, 3(7), 683-685 (2011-06-28)
The insulinomimetic activity of a Zn(ii) complex is reported. The effects of the Zn(ii) complex with ascorbic acid (Vitamin C; VC), methylmethionine sulfonium chloride (Vitamin U; VU) and l-carnitine were assessed in diet-induced metabolic syndrome model rats. Zn(VU)(2)Cl(2) and Zn(VC)Cl(2)
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