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Merck
CN

61793

SAFC

2-酮-D-葡萄糖

≥98.0% (TLC)

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别名:
D-葡萄糖醛酮
经验公式(希尔记法):
C6H10O6
CAS号:
分子量:
178.14
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25

质量水平

100
200

检测方案

≥98.0% (TLC)

形式

solid

颜色

white to beige

储存温度

2-8°C

SMILES字符串

OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)C=O

InChI

1S/C6H10O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,4-6,8,10-12H,2H2/t4-,5-,6-/m1/s1

InChI key

DCNMIDLYWOTSGK-HSUXUTPPSA-N

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应用

2-酮基-D-葡萄糖(D-葡萄糖酮)是导致抗生素cortalcerone的次级代谢途径的关键中间体。 D-葡萄糖酮是一种底物,可用于识别、区分和表征己糖激酶。

生化/生理作用

2-酮基-D-葡萄糖是次级代谢途径的关键中间体,导致β抗生素吡喃酮cortalcerone。这种抗生素能保护真菌免受细菌的侵害。吡喃糖2氧化酶对d-葡萄糖的酶促氧化产生2-酮基-D-葡萄糖,被认为是稀有糖。

包装

无底玻璃瓶。内含物装在插入的融合锥内。

其他说明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

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Wenhui Zhang et al.
Journal of the American Chemical Society, 134(28), 11511-11524 (2012-06-02)
Pathways in the degradation of the C(6) 1,2-dicarbonyl sugar (osone) D-glucosone 2 (D-arabino-hexos-2-ulose) in aqueous phosphate buffer at pH 7.5 and 37 °C have been investigated by (13)C and (1)H NMR spectroscopy with the use of singly and doubly (13)C-labeled
Stefan Freimund et al.
Carbohydrate research, 339(2), 217-220 (2003-12-31)
The composition of the 2-keto aldoses D-glucosone (1), 6-deoxy-D-glucosone (2), D-allosone (3), and D-galactosone (4) in organic solvents has been determined using NMR spectroscopy. Whereas these keto aldoses form mixtures with up to 15 different isomers in water, the number
Kunchala Rungsrisuriyachai et al.
Archives of biochemistry and biophysics, 483(1), 10-15 (2009-01-17)
The flavin-dependent pyranose 2-oxidase catalyzes the oxidation of d-glucose and other pyranoses at the C2 atom to yield 2-keto-sugars and hydrogen peroxide. Here, the steady-state kinetic mechanism of the enzyme from Trametes ochracea was investigated as a function of pH.
A Araki
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 34(9), 716-720 (1998-02-12)
Increased oxidative stress in diabetes mellitus has been implicated in the pathogenesis of diabetic complications. Both an increase in reactive oxygen free radical species (ROS) and a decrease in the antioxidant defense mechanism lead to the increase in oxidative stress
Torbjörn Linden et al.
Kidney international, 62(2), 697-703 (2002-07-12)
Bioincompatible glucose degradation products (GDPs) in fluids for peritoneal dialysis (PD) develop during sterilization and storage. Their biological activity has successfully been monitored through the use of various in vitro methods but their molecular and chemical nature is less well

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