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Merck
CN

54880

3-羟基苄肼 二盐酸盐

≥98.0% (HPLC)

别名:

α-肼基-间-甲酚 二盐酸盐, 3-(肼基甲基)苯酚 二盐酸盐, NSD-1015

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关于此项目

线性分子式:
HOC6H4CH2NHNH2 · 2HCl
化学文摘社编号:
81012-99-9
分子量:
211.09
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
24878937
EC Number:
279-659-3
Beilstein/REAXYS Number:
9282965
MDL number:
MFCD00044695

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产品名称

3-羟基苄肼 二盐酸盐, ≥98.0% (HPLC)

form

solid

InChI key

ONOJPUDFIOEGCX-UHFFFAOYSA-N

InChI

1S/C7H10N2O.2ClH/c8-9-5-6-2-1-3-7(10)4-6;;/h1-4,9-10H,5,8H2;2*1H

SMILES string

Cl[H].Cl[H].NNCc1cccc(O)c1

assay

≥98.0% (HPLC)

mp

137-140 °C
138-140 °C (lit.)

solubility

H2O: 50 mg/mL, slightly hazy, faintly yellow

Quality Level

100

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相关类别

Biochem/physiol Actions

L-芳香族氨基酸脱羧酶抑制剂；穿过血脑屏障。
L-芳香族氨基酸脱羧酶抑制剂；穿过血脑屏障。还可通过形成该辅因子的3-羟基苄基腙，还抑制GABA转氨酶以及其他需要磷酸吡哆醛的酶。

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCBT7147
BCBG5065V
BCBB1136V
BCBB1136
1445429

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Dystonia represents the third most common movement disorder in humans. At least 15 genetic loci (DYT1-15) have been identified and some of these genes have been cloned. TOR1A (formally DYT1), the gene responsible for the most common primary hereditary dystonia
Adrian M Russo et al.
Behavioural brain research, 359, 918-926 (2018-06-24)
Autism spectrum disorder (ASD) is a heterogeneous and highly heritable condition with multiple aetiologies. Although the biological mechanisms underlying ASD are not fully understood, evidence suggests that dysregulation of serotonergic systems play an important role in ASD psychopathology. Preclinical models
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