53370
L-组氨酸 单盐酸盐 一水合物
≥99.0% (AT)
别名:
L-α-氨基-β-（4-咪唑基）丙酸 单盐酸盐
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关于此项目
经验公式（希尔记法）:
C6H9N3O2 · HCl · H2O
化学文摘社编号:
分子量:
209.63
UNSPSC Code:
12352209
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4168261
产品名称
L-组氨酸 单盐酸盐 一水合物, ≥99.0% (AT)
InChI key
CMXXUDSWGMGYLZ-XRIGFGBMSA-N
SMILES string
O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI
1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
assay
≥99.0% (AT)
form
solid
optical activity
[α]20/D +9.5±0.5°, c = 5% in 5 M HCl
impurities
≤0.3% foreign amino acids
mp
254 °C (dec.) (lit.)
solubility
H2O: 1 g/10 mL, clear, colorless (hot)
anion traces
sulfate (SO42-): ≤100 mg/kg
cation traces
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
NH4+: ≤500 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
Quality Level
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Biochem/physiol Actions
L-组氨酸可由ATP、5-磷酸核糖-1-焦磷酸（PRPP）和谷氨酰胺生物合成。这种必需氨基酸可被组氨酸酶、尿苷酶和咪唑酮丙酸酶降解为谷氨酸；它也是组氨酸脱羧酶作用的组胺前体。
General description
L-组氨酸是一种亲水性必需氨基酸，其具有含有咪唑基的碱性侧链。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Biochemistry, 3rd. ed. (New York, NY)
Stryer, L., W.H. Freeman
Biochemistry (3rd Edition), 19-20 (1988)
Textbook of Biochemistry with Clinical Correlations, 5th ed. (New York, NY)
Devlin, T. M., ed., Wiley-Liss
Biochemistry (5th Edition), 97-97 (2002)
Sean E Lehman et al.
Journal of pharmaceutical sciences, 110(5), 1948-1957 (2021-01-17)
Protein aggregation can affect the quality of protein-based therapeutics. Attempting to unravel factors influencing protein aggregation involves systematic studies. These studies often include sodium azide or similar preservatives in the aggregation buffer. This work shows effects of azide on aggregation
Karla Viridiana Castro-Cerritos et al.
Bio-protocol, 7(23), e2634-e2634 (2017-12-05)
Elucidating how a population of non-growing bacteria generates mutations improves our understanding of phenomena like antibiotic resistance, bacterial pathogenesis, genetic diversity and evolution. To evaluate mutations that occur in nutritionally stressed non-growing bacteria, we have employed the strain B. subtilis
Martin Maldonado et al.
Neurochemistry international, 85-86, 31-39 (2015-05-06)
The effect of reserpine on histamine (HA) and tele-methylhistamine (N(τ)-MHA) in hypothalamus and cortex of rats was analyzed and compared to catecholamines. IP injection of reserpine (5 mg/kg) confirmed the effectiveness of reserpine treatment on noradrenaline and dopamine levels. Our in-vitro
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