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Merck
CN

52824

Sigma-Aldrich

(9Z)-β-胡萝卜素

≥90.0% (HPLC)

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别名:
(9Z)-β-β-胡萝卜素, 9-顺式-β-胡萝卜素, 新-β-胡萝卜素
经验公式(希尔记法):
C40H56
CAS号:
分子量:
536.87
Beilstein:
3227021
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.32

质量水平

检测方案

≥90.0% (HPLC)

形式

solid

脂质类型

unsaturated FAs

储存温度

−20°C

SMILES字符串

CC1=C(\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1

InChI

1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21-,34-22+

InChI key

OENHQHLEOONYIE-BVZAMQQESA-N

生化/生理作用

(9Z)-β-胡萝卜素或9-顺式-β-胡萝卜素是人肠粘膜中的9-顺式视黄酸前体。 9-顺式视黄酸是核受体和视黄醇 X 受体(RXR)的配体。 9-顺式-β-胡萝卜素参与基因调控。它主要存在于肝脏中。 9--β-胡萝卜素补充物可抑制动脉粥样硬化发展。 9--β-胡萝卜素可能有助于恢复色素性视网膜炎(RP)和视网膜营养不良患者的感光细胞。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Treatment With 9-cis beta-Carotene-Rich Powder in Patients With Retinitis Pigmentosa: A Randomized Crossover Trial
Rotenstreich Y, et al.
JAMA Ophthalmology, 131(8), 985-992 (2013)
Effects of thermal processing on trans-cis-isomerization of β-carotene in carrot juices and carotene-containing preparations.
Marx, M., et al.
Food Chemistry, 83, 609-617 (2003)
T Toba et al.
Life sciences, 61(8), 839-845 (1997-01-01)
The aim of the present study was to determine to what extent 9-cis beta-carotene, one of the most abundant naturally-occurring cis-isomers of beta-carotene, can inhibit the growth of cervical dysplasia-derived cells in comparison with all-trans beta-carotene. We found that 9-cis
Synthetic 9-cis-beta-carotene inhibits photoreceptor degeneration in cultures of eye cups from rpe65rd12 mouse model of retinoid cycle defect
Sher I, et al.
Scientific Reports, 8(1), 6130-6130 (2018)
W Stahl et al.
Clinical chemistry, 39(5), 810-814 (1993-05-01)
The analysis of beta-carotene and lycopene, the two predominant carotenoids in human serum and tissues, was extended to the level of geometrical (cis-trans) isomers by using an improved reversed-phase HPLC methodology. We separated five geometrical isomers of beta-carotene and seven

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