检测方案
≥98.5% (HPLC)
形式
powder
颜色
white
适用性
complies for H-NMR
应用
cell analysis
储存温度
−20°C
SMILES字符串
O=C1C2(C)C(O2)C(C3=CC=CC=C31)=O
InChI
1S/C11H8O3/c1-11-9(13)7-5-3-2-4-6(7)8(12)10(11)14-11/h2-5,10H,1H3
InChI key
NNUKDUBCRRYXDC-UHFFFAOYSA-N
生化/生理作用
维生素K代谢的代谢产物。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Nicole Jasmin Mueller et al.
Organic & biomolecular chemistry, 7(6), 1115-1119 (2009-03-06)
Three FMN-dependent oxidoreductases, YcnD and YhdA from Bacillus subtilis and Lot6p from Saccharomyces cerevisiae, oxidised alpha,beta-unsaturated carbonyl compounds and a thioether, respectively, to furnish the corresponding racemic epoxides or sulfoxide, respectively. The mechanism of this enzyme-mediated (rather than enzyme-catalysed) oxidation
A Brunmark et al.
Free radical biology & medicine, 5(3), 133-143 (1988-01-01)
The oxidation of various quinones by H2O2 results in quinone epoxide formation. The yield of epoxidation is inversely related to the degree of methyl substitution of the quinone and seems not to be dependent on the redox potential of the
Toru Kitano et al.
Biological & pharmaceutical bulletin, 35(4), 617-623 (2012-04-03)
We investigated the cytotoxicity of eight vitamin K3 (VK3) analogs against neuroblastoma cell lines (IMR-32, LA-N-1, NB-39, and SK-N-SH) and normal cell lines (human umbilical vein endothelial cells (HUVEC) and human dermal fibroblasts (HDF)) using a 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay.
Synthesis, thiol-mediated reactive oxygen species generation profiles and anti-proliferative activities of 2,3-epoxy-1,4-naphthoquinones.
Dharmaraja, A.T., et al
MedChemComm, 3, 219-224 (2012)
The Active Site of Vitamin K and the Role of the Vitamin K-Dependent Carboxylase.
Naganathan, S., et al.
Journal of the American Chemical Society, 116, 9831-9839 (1994)
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