推荐产品
生物来源
Bacillus brevis
质量水平
方案
~90% (HPLC)
表单
powder
杂质
≤5% water
颜色
white to off-white
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
cell membrane | interferes
enzyme | inhibits
储存温度
2-8°C
SMILES字符串
CC(C)C[C@@H]1NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]4CCCN4C(=O)[C@@H](Cc5ccccc5)NC1=O)C(C)C)C(C)C
InChI key
IUAYMJGZBVDSGL-JYFSIOBESA-N
一般描述
Chemical structure: peptide
应用
Gramicidin is a naturally occuring polypeptide antibiotic. It functions as a transmembrane ion channel and is used for studies on phospholipid bilayer membrane fluidity measured by lateral diffusion.
生化/生理作用
Gramicidin′s bactericidal activity is a result of increasing the permeability of the bacterial cell membrane. This allows inorganic monovalent cations to travel through unrestricted which thereby destroys the ion gradient between the cytoplasm and the extracellular environment .
Naturally occuring polypeptide antibiotic with Tyr at position 11; functions as a transmembrane ion channel.
包装
10mg
其他说明
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place. Keep in a dry place.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
G.A. Brewer
Anal. Profiles Drug Subst., 8, 179-179 (1979)
Dong Hyeon Lee et al.
Yonsei medical journal, 49(3), 459-471 (2008-06-27)
This study examined the expression and function of inward rectifier K(+) channels in cultured rat hepatic stellate cells (HSC). The expression of inward rectifier K(+) channels was measured using real-time RT-PCR, and electrophysiological properties were determined using the gramicidin-perforated patch-clamp
Physiology and Pathology of Chloride Transporters and Channels in the Nervous System: From Molecules to Diseases.
Francisco J. Alvarez-Leefmans; Eric Delpire
Physiology and Pathology of Chloride Transporters and Channels in the Nervous System: From Molecules to Diseases, 142-142 (2009)
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