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Merck
CN

50644

Sigma-Aldrich

N-羟乙酰神经氨酸

≥95% (HPLC)

别名:

Neu5Glc, NeuNGl

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About This Item

经验公式(希尔记法):
C11H19NO10
CAS号:
分子量:
325.27
Beilstein:
1716828
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:

生物来源

synthetic

质量水平

方案

≥95% (HPLC)

表单

powder

储存温度

−20°C

SMILES字符串

[H][C@]1(O[C@@](O)(C[C@H](O)[C@H]1NC(=O)CO)C(O)=O)[C@H](O)[C@H](O)CO

InChI

1S/C11H19NO10/c13-2-5(16)8(18)9-7(12-6(17)3-14)4(15)1-11(21,22-9)10(19)20/h4-5,7-9,13-16,18,21H,1-3H2,(H,12,17)(H,19,20)/t4-,5+,7+,8+,9+,11-/m0/s1

InChI key

FDJKUWYYUZCUJX-AJKRCSPLSA-N

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应用

甘氨酰神经氨酸,一种非人类乳汁和初乳的成分,被用作引用来分析泌乳期中甘氨酸的变化。甘氨酰神经氨酸是一种异种抗原,在异种移植过程中参与抗原反应(抗体介导的超急性排斥反应)。

其他说明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。
N-羟乙酰神经氨酸在大鼠和小鼠肝脏中生物合成的调节
销售限制可能适用

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A Lepers et al.
European journal of biochemistry, 193(3), 715-723 (1990-11-13)
The relative contribution of N-glycoloyl-beta-D-neuraminic acid (Neu5Gc) to total sialic acids expressed in mouse and rat liver glycoconjugates was found to be 95% and 11%, respectively. This considerable difference in sialic acid composition made these two tissues suitable models for
D C Hurum et al.
Journal of dairy science, 95(3), 1152-1161 (2012-03-01)
Sialic acid determination in an infant formula presents many challenges, including efficient sialic acid release from glycoconjugates, effective sample preparation, and rugged chromatography. This work compares 2 chromatographic assays developed for determination of sialic acids in infant formula. Prior to
On the differential sialic acid specificity of lectins from different parts of Saraca indica.
Bishnu P Chatterjee et al.
Advances in experimental medicine and biology, 705, 213-228 (2011-05-28)
Nabin B Basnet et al.
Xenotransplantation, 17(6), 440-448 (2010-12-17)
A number of carbohydrate structures apart from Galα1-3Galβ1-4GlcNAc (Gal) have been implicated as potential xenoantigens. Epitopes of another carbohydrate structure, namely N-glycolylneuraminic acid (NeuGc), are widely expressed on the surfaces of endothelial cells of all mammals, except humans, and are
Eiki Maeda et al.
Analytical chemistry, 84(5), 2373-2379 (2012-03-08)
Minor N-linked glycans containing N-glycolylneuraminic acid residues and/or α-Gal epitopes (i.e., galactose-α1,3-galactose residues) have been reported to be present in recombinant monoclonal antibody (mAb) therapeutics. These contaminations are due to their production processes using nonhuman mammalian cell lines in culture

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