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Merck
CN

50637

Sigma-Aldrich

癸酰基- L -肉碱

≥94.0% (HPLC)

别名:

L -肉碱癸酸酯, C10-肉碱, (2 R )-3-羧基- N N N -三甲基-2-[(1-氧代十二烷基)氧基]-1-丙胺 内盐

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About This Item

经验公式(希尔记法):
C17H33NO4
CAS号:
分子量:
315.45
Beilstein:
4145305
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.26

质量水平

检测方案

≥94.0% (HPLC)

形式

powder or crystals

旋光性

[α]/D -15±3°, c = 1 in H2O

杂质

≤10% water

官能团

ester

储存温度

2-8°C

SMILES字符串

C[N+](C)(C)C[C@H](OC(CCCCCCCCC)=O)CC([O-])=O

InChI

1S/C17H33NO4/c1-5-6-7-8-9-10-11-12-17(21)22-15(13-16(19)20)14-18(2,3)4/h15H,5-14H2,1-4H3/t15-/m1/s1

InChI key

LZOSYCMHQXPBFU-OAHLLOKOSA-N

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生化/生理作用

癸酰肉碱可用于诊断脂肪酸氧化障碍和区分中链酰基辅酶A脱氢酶(MCAD)缺乏症和氧化障碍的生化表型。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Proceedings of the National Academy of Sciences of the United States of America, 111(29), 10761-10766 (2014-07-09)
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Biophysical journal, 118(5), 1032-1043 (2020-02-07)
Excessive accumulation of acylcarnitines (ACs), often caused by metabolic disorders, has been associated with obesity, arrhythmias, cardiac ischemia, insulin resistance, etc. Mechanisms whereby elevated ACs might contribute to pathophysiological effects remain largely unexplored. We have aimed to gain insight into
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Insulin resistance (IR) predisposes to type 2 diabetes and cardiovascular disease but its causes are incompletely understood. Metabolic challenges like the oral glucose tolerance test (OGTT) can reveal pathogenic mechanisms. We aimed to discover associations of IR with metabolite trajectories

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