50227
D -荧光素 钾盐
≥98.0% (HPLC)
别名:
( S )-2-（6-羟基-2-苯并噻唑基）-2-噻唑啉-4-羧酸 钾盐, 4,5-二氢-2-（6-羟基-2-苯并噻唑基）-4-噻唑羧酸 钾盐, 萤火虫荧光素 钾盐
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关于此项目
经验公式（希尔记法）:
C11H7KN2O3S2
化学文摘社编号:
分子量:
318.41
Beilstein:
5416262
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.32
质量水平
方案
≥98.0% (HPLC)
表单
powder or crystals
溶解性
water: soluble
储存温度
−20°C
SMILES字符串
[K+].Oc1ccc2nc(sc2c1)C3=N[C@H](CS3)C([O-])=O
InChI
1S/C11H8N2O3S2.K/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;/h1-3,7,14H,4H2,(H,15,16);/q;+1/p-1/t7-;/m1./s1
InChI key
UMBKGTQQGYPQBE-OGFXRTJISA-M
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应用
D-萤光素可用作基于荧光素酶(EC 1.13.12.7)的生物发光成像和基于细胞的高通量筛选应用的底物。D-荧光素和萤火虫荧光素酶组成的试剂可以测量ATP。D-荧光素可以作为G蛋白偶联受体-35(GPR35)的部分激动剂使用和研究。
包装
无底玻璃瓶。内含物在插入的融合锥体内。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Mayu Yasunaga et al.
BMC biotechnology, 17(1), 54-54 (2017-06-24)
Three-dimensional (3D) spheroids are frequently used in toxicological study because their morphology and function closely resemble those of tissue. As these properties are maintained over a long term, repeated treatment of the spheroids with a test object is possible. Generally
Bruce R Branchini et al.
Scientific reports, 8(1), 5990-5990 (2018-04-18)
Effective methods for monitoring eukaryotic gene expression and regulation based on bioluminescence - the emission of light by living organisms - are well established. Typically, the expression of a gene of interest is reported on with high sensitivity and over
Yun-Jung Chiang et al.
Oncogene, 38(9), 1432-1447 (2018-09-30)
High-frequency relapse remains a clinical hurdle for complete remission of T-cell acute lymphoblastic leukemia (T-ALL) patients, with heterogeneous dysregulated signaling profiles-including of Raf-MEK-ERK and Akt-mTORC1-S6K signaling pathways-recently being implicated in disease outcomes. Here we report that GM-CSF/IL-3/IL-5 receptor common β-chain-associated
A B Madhankumar et al.
PloS one, 13(1), e0181529-e0181529 (2018-01-06)
Peripheral nerve sheath tumors are benign tumors that have the potential to transform into malignant peripheral nerve sheath tumors (MPNSTs). Interleukin-13 receptor alpha 2 (IL13Rα2) is a cancer associated receptor expressed in glioblastoma and other invasive cancers. We analyzed IL13Rα2
Yimao Zhang et al.
Molecular imaging, 11(6), 499-506 (2012-10-23)
Bioluminescence imaging (BLI) detects light generated by luciferase-mediated oxidation of substrate and is used widely for evaluating transgene expression in cell-based assays and in vivo in relevant preclinical models. The most commonly used luciferase for in vivo applications is firefly
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