跳转至内容
Merck
CN
所有图片(3)

文件

安全信息

483R-1

Sigma-Aldrich

p40 (ZR8) Rabbit Monoclonal Antibody

登录查看公司和协议定价
所有图片(3)

About This Item

UNSPSC代码:
12352203

生物来源

rabbit

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

ZR8

描述

For In Vitro Diagnostic Use in Select Regions

形式

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (483R-14)
vial of 0.1 mL concentrate, Research Use Only (483R-14-RUO)
vial of 0.5 mL concentrate (483R-15)
vial of 1.0 mL concentrate (483R-16)
vial of 1.0 mL concentrate, Research Use Only (483R-16-RUO)
vial of 1.0 mL pre-dilute, Research Use Only (483R-17-RUO)
vial of 1.0 mL pre-dilute, ready to use (483R-17)
vial of 25.0 mL pre-dilute, ready-to-use (483R-10)
vial of 25.0 mL pre-dilute, ready-to-use, Research Use Only (483R-10-RUO)
vial of 7.0 mL pre-dilute, ready to use (483R-18)
vial of 7.0 mL pre-dilute, ready to use, Research Use Only (483R-18-RUO)

制造商/商品名称

Cell Marque

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable (1:100-1:200 (concentrated))

同位素/亚型

IgG

控制

lung (squamous cell carcinoma), prostate, urothelial carcinoma

运输

wet ice

储存温度

2-8°C

可视化

nuclear

相关类别

一般描述

p40 is an isoform of p63, a transcription factor that regulates many cell activities, including cell proliferation, maintenance, and differentiation. It performs as a sensitive and specific tool for aiding in the identification of squamous cell carcinoma of the lung. In addition to its utility as a squamous differentiation marker, p40 has also been proven to be a valuable marker for highlighting myoepithelial and basal cell populations in prostate, breast, skin, and salivary gland.1-5 Strong p40 expression is frequently observed in esophageal cancerous squamous lesions.6 Immunohistochemical detection of p40 can also be helpful in identifying urothelial carcinoma.7 In cases of prostate carcinoma, p40 is almost always found to be negative for basal cell staining.8

质量

  • United States - IVD
  • Canada - RUO
  • European Union - IVD
  • Japan - RUO

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Not finding the right product?  

Try our 产品选型工具.

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Khairunisa Ahmad Affandi et al.
Journal of pathology and translational medicine, 52(5), 283-289 (2018-09-22)
Lung cancer is the third most common cancer worldwide. With major advances in the molecular testing of lung cancers and the introduction of targeted therapies, the distinction between adenocarcinoma and squamous cell carcinoma as well as pathologic subtyping has become
Hermann Brustmann
Pathology research international, 2015, 897927-897927 (2015-04-09)
Immunohistochemistry is important for the accurate diagnosis of basal cells in atypical glandular proliferations of the prostate. p40, an isoform of p63, may be an adjunct to a marker panel in this setting. Biopsies of 68 patients were analyzed by
Helene Geddert et al.
Human pathology, 34(9), 850-856 (2003-10-17)
p63, a member of the p53 gene family, is known to encode functionally antagonistic protein isoforms. Although transactivating protein isoforms display p53-like functions, deltaNp63 isoforms act toward p53 in a dominant negative way. Using immunohistochemistry, we examined the expression of
Ritika Walia et al.
The Indian journal of medical research, 146(1), 42-48 (2017-11-24)
Accurate histopathological subtyping of non-small cell lung carcinoma (NSCLC) is essential for targeted therapeutic agents. Immunohistochemistry (IHC) is helpful in identification of different tumour subtypes. In this study two marker approaches, one each for glandular and squamous cell differentiation was
Tamar C Brandler et al.
Cancer cytopathology, 122(6), 468-473 (2014-04-09)
GATA3 (GATA-binding protein 3) expression in urothelial carcinoma (UC) and mammary carcinomas has been recently reported. However, to the authors' knowledge, studies examining GATA3 staining of metastatic UC (MUC) in cytology specimens are lacking. Delta Np63 (p40) has been shown
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门