形式
solid
质量水平
分子量
average mol wt 150,000
组成
(FITC:Glucose = 1:160)
标记范围
~0.004 mol/mol FITC glucose
溶解性
H2O: 25 mg/mL, slightly hazy, very deep yellow-orange
荧光
λex 492 nm; λem 518 nm in 0.1 M phosphate pH 8.0
储存温度
2-8°C
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应用
用异硫氰酸荧光素标记的葡聚糖可用于动物的灌注研究。
荧光素异硫氰酸酯-葡聚糖（FITC-葡聚糖150）可用作荧光探针以研究细胞渗透性。FITC-Dextran 150可用于研究影响血脑屏障（BBB）和微血管结构渗透性的过程。FITC-Dextran 150可用于荧光微淋巴造影。
其他说明
通常用作炎症研究中的大分子荧光染料
警示用语：
Warning
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
D M Gawlowski et al.
Microvascular research, 37(1), 1-15 (1989-01-01)
Fluorescein-labeled dextran MW 150K (FITC-Dx 150) is commonly utilized as a macromolecular fluorochrome in inflammatory studies. We examined the influence of FITC-Dx 150 on leukocyte activity as assessed by adherence to cheek pouch microvessels. Transcapillary exchange was evaluated as fluorochrome
Fátima Z G A Cyrino et al.
Clinical and experimental pharmacology & physiology, 31(3), 159-162 (2004-03-11)
1. The present study was designed to evaluate the effect of micronization on the protective effect of the purified flavonoid fraction (MPFF) on increases in macromolecular permeability induced by ischaemia-reperfusion in the hamster cheek pouch microcirculation. 2. Male hamsters (Mesocricetus
Haruo Aramoto et al.
American journal of physiology. Heart and circulatory physiology, 287(4), H1590-H1598 (2004-05-25)
Vascular endothelial growth factor (VEGF) induces mild vasodilation and strong increases in microvascular permeability. Using intravital microscopy and digital integrated optical intensity image analysis, we tested, in the hamster cheek pouch microcirculation, the hypothesis that differential signaling pathways in arterioles
Neil Y C Lin et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(12), 5399-5404 (2019-03-06)
Three-dimensional renal tissues that emulate the cellular composition, geometry, and function of native kidney tissue would enable fundamental studies of filtration and reabsorption. Here, we have created 3D vascularized proximal tubule models composed of adjacent conduits that are lined with
Nikolce Gjorevski et al.
Lab on a chip, 20(18), 3365-3374 (2020-08-08)
The multiphasic etiology of tissue inflammation and the fundamental immunological differences between species render inflammatory pathologies difficult to recapitulate in animal models, and account for the paucity of therapies that are successfully translated from rodents to humans. Here, we present
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