产品名称
异硫氰酸荧光素-葡聚糖, average mol wt 150,000, (FITC:Glucose = 1:160)
form
solid
mol wt
average mol wt 150,000
composition
(FITC:Glucose = 1:160)
extent of labeling
~0.004 mol/mol FITC glucose
solubility
H2O: 25 mg/mL, slightly hazy, very deep yellow-orange
fluorescence
λex 492 nm; λem 518 nm in 0.1 M phosphate pH 8.0
storage temp.
2-8°C
Quality Level
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Application
用异硫氰酸荧光素标记的葡聚糖可用于动物的灌注研究。
荧光素异硫氰酸酯-葡聚糖(FITC-葡聚糖150)可用作荧光探针以研究细胞渗透性。FITC-Dextran 150可用于研究影响血脑屏障(BBB)和微血管结构渗透性的过程。FITC-Dextran 150可用于荧光微淋巴造影。
Other Notes
通常用作炎症研究中的大分子荧光染料
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
D M Gawlowski et al.
Microvascular research, 37(1), 1-15 (1989-01-01)
Fluorescein-labeled dextran MW 150K (FITC-Dx 150) is commonly utilized as a macromolecular fluorochrome in inflammatory studies. We examined the influence of FITC-Dx 150 on leukocyte activity as assessed by adherence to cheek pouch microvessels. Transcapillary exchange was evaluated as fluorochrome
Fátima Z G A Cyrino et al.
Clinical and experimental pharmacology & physiology, 31(3), 159-162 (2004-03-11)
1. The present study was designed to evaluate the effect of micronization on the protective effect of the purified flavonoid fraction (MPFF) on increases in macromolecular permeability induced by ischaemia-reperfusion in the hamster cheek pouch microcirculation. 2. Male hamsters (Mesocricetus
Takayuki Ishii et al.
Brain research, 1321, 164-168 (2010-01-26)
Ischemia-reperfusion injury is induced by recovery of blood flow after ischemia. This phenomenon is a main cause of ischemic brain injury. The integrity of the blood-brain barrier (BBB) fails after cerebral ischemia and reperfusion. Further elucidation of this phenomenon promotes
A Bollinger et al.
Lymphology, 40(2), 52-62 (2007-09-15)
Fluorescence microlymphography (FML) is an almost atraumatic technique used to visualize the superficial skin network of initial lymphatics through the intact skin of man. Visualization was performed with an incident light fluorescence microscope following subepidermal injection of minute amounts of
Haruo Aramoto et al.
American journal of physiology. Heart and circulatory physiology, 287(4), H1590-H1598 (2004-05-25)
Vascular endothelial growth factor (VEGF) induces mild vasodilation and strong increases in microvascular permeability. Using intravital microscopy and digital integrated optical intensity image analysis, we tested, in the hamster cheek pouch microcirculation, the hypothesis that differential signaling pathways in arterioles
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