46943
Fluorescein dilaurate
suitable for fluorescence, ≥97.0% (HPCE)
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关于此项目
经验公式（希尔记法）:
C44H56O7
化学文摘社编号:
分子量:
696.91
UNSPSC Code:
12352106
NACRES:
NA.32
PubChem Substance ID:
EC Number:
230-764-2
Beilstein/REAXYS Number:
6034843
MDL number:
InChI key
MYTRGBGGRICZGN-UHFFFAOYSA-N
InChI
1S/C44H56O7/c1-3-5-7-9-11-13-15-17-19-25-41(45)48-33-27-29-37-39(31-33)50-40-32-34(49-42(46)26-20-18-16-14-12-10-8-6-4-2)28-30-38(40)44(37)36-24-22-21-23-35(36)43(47)51-44/h21-24,27-32H,3-20,25-26H2,1-2H3
SMILES string
CCCCCCCCCCCC(=O)Oc1ccc2c(Oc3cc(OC(=O)CCCCCCCCCCC)ccc3C24OC(=O)c5ccccc45)c1
assay
≥97.0% (HPCE)
form
powder
solubility
ethanol: soluble
fluorescence
λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0 (esterase)
suitability
suitable for fluorescence
Quality Level
Application
Fluorescein dilaurate is suitable as fluorogenic substrate for esterases/lipases and used in the pancreolauryl test for chronic pancreatitis.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
F Seibold et al.
Journal of clinical gastroenterology, 22(3), 202-206 (1996-04-01)
Pancreatic autoantibodies (PABs) are found in 31% of patients with Crohn's disease (CD), but they do not correlate with the activity of intestinal disease or the incidence of acute pancreatitis. Exocrine pancreatic insufficiency has been observed in patients with CD.
Maria Beatriz Di Carlo et al.
Acta gastroenterologica Latinoamericana, 40(2), 128-133 (2010-07-22)
The pancreas is a mixed gland that takes part in the digestion of nutrients and in the homeostasis ofglycemia. Chronic pancreopathy is the cause of secretory insufficiency, characterized by an inflammatory process that leads to fibrosis of the pancreas, with
D A Elphick et al.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 5(2-3), 196-200 (2005-04-26)
The urine pancreolauryl ratio (uPLR) and, more recently, the faecal pancreatic elastase-1, are widely used for the noninvasive diagnosis of exocrine pancreatic insufficiency. Both tests have previously been validated against 'gold standard' tests of pancreatic function, but their use in
Z Wójcik et al.
Polski tygodnik lekarski (Warsaw, Poland : 1960), 50(1-35), 791-793 (1995-01-01)
Fifteen patients with chronic pancreatitis were qualified for surgical treatment on the basis of the results of endoscopic retrograde cholangiopancreatography, pancreolauryl test and glucose tolerance test. Significant changes according to Cambridge scale correlated with exocrine-endocrine pancreatic failure. In patients with
E Małecka-Panas et al.
Polskie Archiwum Medycyny Wewnetrznej, 94(4), 315-323 (1995-10-01)
The aim of the presented study was a comparative evaluation of the three indirect pancreatic function tests: pancreolauryl-test (PLT), NBT-PABA test and faecal chymotrypsin (CH) efficacy in detecting pancreatic exocrine function impairment in advanced chronic pancreatitis (acp). 30 patients with
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