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Merck
CN
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文件

安全信息

46133

Supelco

金霉素盐酸盐 盐酸盐

VETRANAL®, analytical standard

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别名:
金霉素 盐酸盐
经验公式（希尔记法）:
C22H23ClN2O8 · HCl
CAS号:
64-72-2
分子量:
515.34
Beilstein:
3858364
EC 号:
200-591-7
MDL编号:
MFCD00082440
UNSPSC代码:
41116107
PubChem化学物质编号:
329757081
E编号:
E702
NACRES:
NA.24

等级

analytical standard

质量水平

200

Agency

EPA 1694

产品线

VETRANAL®

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

210-215 °C (dec.) (lit.)

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

应用

cleaning products
clinical
cosmetics
environmental
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

格式

neat

作用机制

protein synthesis | interferes

储存温度

2-8°C

SMILES字符串

Cl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O

InChI

1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1

InChI key

CBHYYLPALVVVEY-LYNLVHCPSA-N

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相关类别

一般描述

Chemical structure: tetracycline

法律信息

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Warning

危险分类

Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

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Hui Fu et al.
Wei sheng yan jiu = Journal of hygiene research, 41(2), 282-286 (2012-05-23)
To develop a method for determination of the Metronidazole, Chlortetracycline hydrochloride, Oxytetracycline dihydrate, Minocycline hydrochloride, Erythromycin and Tetracycline hydrochloride in disinfection products by high performance liquid chromatography tandem mass spectrometry(LC-MS/MS). Samples were extracted by methanol and filtered through 0.45 microm
Zhizhong Li et al.
Journal of biochemical and molecular toxicology, 26(9), 331-336 (2012-06-26)
In this work, the interaction of chlortetracycline with bovine serum albumin (BSA) was investigated by fluorescence spectroscopy, circular dichroism (CD) spectroscopy, and molecular docking. Results indicated that chlortetracycline quenches BSA fluorescence mainly by a static quenching mechanism. The quenching constants
Luxi Dong et al.
Chemosphere, 89(1), 44-51 (2012-06-01)
DNA damage and changes in enzyme activities were used as biomarkers to evaluate the genotoxicity and oxidative stress of tetracycline and chlortetracycline on the earthworm Eisenia fetida. The results showed that both antibiotics induced significant genotoxicity on earthworms in a
Dasong Lin et al.
Environmental pollution (Barking, Essex : 1987), 171, 46-51 (2012-08-08)
This study aims to evaluate toxic effects of exposure to chlortetracycline (CTC) in soil on reproductive endpoints (juvenile counts and cocoon counts), biochemical responses, and genotoxic potentials of the earthworm Eisenia fetida. Results showed that juvenile counts and cocoon counts
Teal M Dreher et al.
Bioresource technology, 125, 65-74 (2012-10-02)
The effects of antimicrobial chlortetracycline (CTC) on the anaerobic digestion (AD) of swine manure slurry using anaerobic sequencing batch reactors (ASBRs) was investigated. Reactors were loaded with manure collected from pigs receiving CTC and no-antimicrobial amended diets at 2.5 g/L/d.
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