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Merck
CN

46133

金霉素盐酸盐 盐酸盐

VETRANAL®, analytical standard

别名:

金霉素 盐酸盐

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关于此项目

经验公式（希尔记法）:
C22H23ClN2O8 · HCl
化学文摘社编号:
64-72-2
分子量:
515.34
NACRES:
NA.24
E Number:
E702
PubChem Substance ID:
329757081
UNSPSC Code:
41116107
EC Number:
200-591-7
MDL number:
MFCD00082440
Beilstein/REAXYS Number:
3858364

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产品名称

金霉素盐酸盐 盐酸盐, VETRANAL®, analytical standard

InChI key

CBHYYLPALVVVEY-LYNLVHCPSA-N

InChI

1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1

SMILES string

Cl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O

grade

analytical standard

agency

EPA 1694

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

210-215 °C (dec.) (lit.)

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

application(s)

cleaning products
clinical
cosmetics
environmental
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

format

neat

mode of action

protein synthesis | interferes

storage temp.

2-8°C

Quality Level

200

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相关类别

General description

Chemical structure: tetracycline

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCH2550
BCCG5799
BCBT9837
BCBR8687V

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Hui Fu et al.
Wei sheng yan jiu = Journal of hygiene research, 41(2), 282-286 (2012-05-23)
To develop a method for determination of the Metronidazole, Chlortetracycline hydrochloride, Oxytetracycline dihydrate, Minocycline hydrochloride, Erythromycin and Tetracycline hydrochloride in disinfection products by high performance liquid chromatography tandem mass spectrometry(LC-MS/MS). Samples were extracted by methanol and filtered through 0.45 microm
Luxi Dong et al.
Chemosphere, 89(1), 44-51 (2012-06-01)
DNA damage and changes in enzyme activities were used as biomarkers to evaluate the genotoxicity and oxidative stress of tetracycline and chlortetracycline on the earthworm Eisenia fetida. The results showed that both antibiotics induced significant genotoxicity on earthworms in a
Menghong Dai et al.
Journal of microbiology (Seoul, Korea), 50(5), 807-812 (2012-11-06)
The present criteria and rules controlling the approval of the use of probiotics are limited to antibiotic resistance patterns and the presence of antibiotic resistance genes in bacteria. There is little information available in the literature regarding the risk of
Lukas Ded et al.
Reproduction (Cambridge, England), 145(3), 255-263 (2013-01-16)
Estrogens play a crucial role in spermatogenesis and estrogen receptor α knock-out male mice are infertile. It has been demonstrated that estrogens significantly increase the speed of capacitation in vitro; however this may lead to the reduction of reproductive potential
Dasong Lin et al.
Environmental pollution (Barking, Essex : 1987), 171, 46-51 (2012-08-08)
This study aims to evaluate toxic effects of exposure to chlortetracycline (CTC) in soil on reproductive endpoints (juvenile counts and cocoon counts), biochemical responses, and genotoxic potentials of the earthworm Eisenia fetida. Results showed that juvenile counts and cocoon counts
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