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Merck
CN

45198

Sigma-Aldrich

肠二醇

≥95.0% (HPLC)

别名:

3,3′-[2,3-双(羟甲基)丁烷-1,4-二基]二酚

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About This Item

经验公式(希尔记法):
C18H22O4
CAS号:
分子量:
302.36
Beilstein:
8997364
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.77
表单:
solid
方案:
≥95.0% (HPLC)

质量水平

方案

≥95.0% (HPLC)

表单

solid

储存温度

2-8°C

SMILES字符串

OCC(Cc1cccc(O)c1)C(CO)Cc2cccc(O)c2

InChI

1S/C18H22O4/c19-11-15(7-13-3-1-5-17(21)9-13)16(12-20)8-14-4-2-6-18(22)10-14/h1-6,9-10,15-16,19-22H,7-8,11-12H2

InChI key

DWONJCNDULPHLV-UHFFFAOYSA-N

相关类别

应用


  • 基于文献的肠道微生物群膳食指数的开发与评价: 该研究评估了肠二醇在塑造肠道微生物群中的潜在作用,提出了一种可能影响微生物多样性和活性的膳食指数(dietary index)。该研究可能引发出针对性的饮食建议,改善肠道健康(Kase et al., 2024).

  • 在尿植物雌激素(urinary phytoestrogen)与哮喘/喘息和肺功能的相关性中性别和吸烟的作用。: 该分析将肠二醇引入植物雌激素中,评估其对呼吸系统健康的影响,揭示了生活方式因素如何调节这些影响的重要见解(Zhang et al., 2024)。

  • 辣椒素和植物木脂素抑制与肥胖相关的炎症性巨噬细胞极化: 研究了肠二醇和其他植物木脂素在调节肥胖炎症过程中的功效,为减轻肥胖相关炎症提供了一条潜在的途径(Poynter et al., 2024)。

  • 咖啡多酚及其在缓解影响二型糖尿病发病因素中的作用: 重点研究了咖啡衍生的多酚,包括肠二醇,探索其在管理和预防二型糖尿病方面的治疗潜力(Chapple et al., 2024)。

  • 微生物酚代谢产物与改善的认知健康有关: 讨论了肠二醇作为膳食酚类物质的微生物代谢产物,如何与增强的认知功能相联系,强调了饮食在心理健康中的重要性(Domínguez-López et al., 2024)。


生化/生理作用

肠二醇被称为“哺乳动物木脂体”,是由植物木脂素经肠道菌群代谢而产生的。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Daniel Hinojosa-Nogueira et al.
Journal of agricultural and food chemistry, 65(20), 4216-4222 (2017-05-06)
Polyphenols are bioactive substances of vegetal origin with a significant impact on human health. The assessment of polyphenol intake and excretion is therefore important. The Folin-Ciocalteu (F-C) method is the reference assay to measure polyphenols in foods as well as
Hongmei Jiang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1012-1013, 106-112 (2016-01-28)
A sensitive and robust method using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was developed for quantitation of 13 phytoestrogens and related metabolites in rat serum samples. A new type of column, the Kinetex core-shell C18 column, was applied for
Alejandro de Athayde Moncorvo Collado et al.
The Journal of membrane biology, 251(4), 593-600 (2018-05-08)
The interaction of enterodiol and the well-described polyphenol epigallocatechin gallate (EGCG) with hepatic membranes has been matter of interest in the last few years. On one hand, EGCG is only able to bind to the phospholipid polar head groups, as
Mingyue Zhang et al.
International journal of environmental research and public health, 12(12), 15110-15117 (2015-12-04)
Exposure to artificial or natural endocrine disruptors, such as bisphenol A (BPA) and phytoestrogens has been demonstrated to have health effects, especially in children. Biomonitoring of BPA and phytoestrogens in human urine can be used to assess the intake levels
Qi Sun et al.
The American journal of clinical nutrition, 105(1), 159-168 (2017-01-05)
Limited knowledge regarding the reproducibility of biomarkers in 24-h urine samples has hindered the collection and use of the samples in epidemiologic studies. We aimed to evaluate the reproducibility of various markers in repeat 24-h urine samples. We calculated intraclass

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