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Merck
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主要文件

安全信息

450R-1

Sigma-Aldrich

Prostein (EP381) Rabbit Monoclonal Primary Antibody

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About This Item

UNSPSC代码:
12352203

生物来源

rabbit

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

EP381, monoclonal

描述

This product is intended for research use only. Not for use in diagnostic procedures.

表单

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate Research Use Only (450R-14-RUO)
vial of 1.0 mL concentrate Research Use Only (450R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (450R-17-RUO)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (450R-18-RUO)

制造商/商品名称

Cell Marque

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)

同位素/亚型

IgG

控制

prostate, prostate carcinoma

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

一般描述

Prostein is a type IIIA transmembrane protein comprising a cleavable signal peptide and 11 transmembrane domains. In vitro studies demonstrate that prostein transcription and expression is androgen responsive. Prostein expression was found to be restricted to tissues of prostatic origin such as non-neoplastic prostate, prostate lesions, and malignant prostate tissues. Due to its high specificity, immunohistochemical detection of prostein may have utility in distinguishing prostatic carcinoma from the carcinomas of bladder, kidney, lung and colorectum.

质量


IVD

IVD

IVD

RUO

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

法规信息

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分析证书(COA)

Lot/Batch Number

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Michael Kalos et al.
The Prostate, 60(3), 246-256 (2004-06-04)
Prostein is a recently described molecule expressed at the mRNA level in a prostate-specific manner. A murine monoclonal antibody was developed, characterized, and used to evaluate the expression of prostein protein in prostatic, other normal tissue and tumor samples. The
Todd Sheridan et al.
The American journal of surgical pathology, 31(9), 1351-1355 (2007-08-28)
Adenocarcinoma of the prostate can present as metastatic carcinoma with no known primary. Prostatic origin can be confirmed in most of these cases by immunohistochemistry for prostate-specific antigen (PSA) and prostate-specific acid phosphatase. In a small subset of high-grade prostate
J Xu et al.
Cancer research, 61(4), 1563-1568 (2001-03-14)
In this report, we describe the application of a systematic, genome-based approach to identify prostein, a novel prostate-specific protein expressed in normal and malignant prostate tissues. Characterization of the prostein gene shows that prostein cDNA encodes a 553-amino acid protein.

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