44977
DISBAC2(3), Voltage Sensitive Probe
≥98% (HPLC)
别名:
5-[3-(1,3-Diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propen-1-ylidene]-1,3-diethyldihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione, Bis(1,3-diethylthiobarbituric acid)trimethine oxonol
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所有图片(1)
About This Item
经验公式（希尔记法）:
C19H24N4O4S2
CAS号:
分子量:
436.55
Beilstein:
1232950
EC 号:
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.32
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质量水平
方案
≥98% (HPLC)
荧光
λex 535 nm; λem 560 nm in DMSO
适用性
complies for Infrared spectrum
储存温度
−20°C
SMILES字符串
CCN1C(=O)C(\C=C\C=C2\C(=O)N(CC)C(=S)N(CC)C2=O)C(=O)N(CC)C1=S
InChI
1S/C19H24N4O4S2/c1-5-20-14(24)12(15(25)21(6-2)18(20)28)10-9-11-13-16(26)22(7-3)19(29)23(8-4)17(13)27/h9-12H,5-8H2,1-4H3/b10-9+
InChI key
VJYNRXFXHKIGLT-MDZDMXLPSA-N
应用
DISBAC2(3), Voltage Sensitive Probe is used for single-cell fluorescence imaging of transmembrane conductance and potential change.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Alexander S Tatikolov et al.
Biophysical chemistry, 107(1), 33-49 (2004-02-12)
Non-covalent interactions between polymethine dyes of various types (cationic and anionic thiacarbocyanines as well as anionic oxonols and tetracyanopolymethines) and human serum albumin (HSA) were studied by means of absorption, fluorescence and circular dichroism (CD) spectroscopies. Complexation with the protein
In situ study of the membrane potential in microvascular endothelial cells using a fluorescent probe.
K Miao et al.
Microvascular research, 48(1), 135-142 (1994-07-01)
N Minami et al.
Journal of neural transmission. General section, 97(1), 65-72 (1994-01-01)
Effects of cyclic AMP on membrane potentials were examined by measuring the changes of bis-oxonol fluorescence in bovine adrenal medullary chromaffin cells. 8-Bromo cyclic AMP (8Br-cAMP) or forskolin caused a gradual and long lasting increase of the fluorescence intensity. The
V Dall'Asta et al.
Experimental cell research, 231(2), 260-268 (1997-03-15)
Confocal laser scanning microscopy (CLSM) was employed to visualize and measure membrane potential changes in several types of cultured adherent cells, such as human fibroblasts, mouse mammary tumor C127 cells, and human saphenous vein endothelial cells, preloaded with the anionic
Flow cytometric analysis of altered mononuclear cell transmembrane potential induced by cyclosporin.
M K Tanner et al.
Cytometry, 14(1), 59-69 (1993-01-01)
Immunosuppression by the fungal metabolite cyclosporin A (CsA) is characterized by functional inhibition, rather than destruction of cells. Because activation of immune cells involves intracellular signalling events associated with modulations of cell transmembrane potential (TMP), we tested the ability of
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