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Merck
CN
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主要文件

安全信息

446R-1

Sigma-Aldrich

Steroidogenic Acute Regulatory Protein (STAR) (EP226) Rabbit Monoclonal Primary Antibody

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About This Item

UNSPSC代码:
12352203

生物来源

rabbit

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

EP226, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions

表单

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (446R-14)
vial of 0.1 mL concentrate Research Use Only (446R-14-RUO)
vial of 0.5 mL concentrate (446R-15)
vial of 1.0 mL concentrate (446R-16)
vial of 1.0 mL concentrate Research Use Only (446R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (446R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (446R-17)
vial of 7.0 mL pre-dilute ready-to-use (446R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (446R-18-RUO)

制造商/商品名称

Cell Marque™

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)

同位素/亚型

IgG

控制

adrenal cortex

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

基因信息

human ... STAR(6770)

一般描述

Steroidogenic Acute Regulatory Protein (STAR) is a sterol transfer protein that is critical for steroidegenesis. Steroidegenesis is the process where steroid hormones are made within specialized cells. STAR controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. Immunohistochemically, STAR is a cytoplasmic marker that is generally localized in the normal and neoplastic cells of steroid hormone producing tissues such as testis and adrenal gland. Due to their low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, this antibody may assist in differentiating sex cord stromal tumors, seminomas and embryonal carcinomas.

质量


IVD
IVD
IVD
RUO

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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S E Pollack et al.
The Journal of clinical endocrinology and metabolism, 82(12), 4243-4251 (1997-12-17)
The rate-limiting step in steroid hormone production in the adrenal cortex and gonads, the translocation of cholesterol from the outer to the inner mitochondrial membranes, is mediated by the steroidogenic acute regulatory protein (StAR). Heretofore, the localization of StAR in
C B Kallen et al.
The Journal of biological chemistry, 273(41), 26285-26288 (1998-10-03)
Steroidogenic acute regulatory protein (StAR) plays a critical role in steroidogenesis by enhancing the delivery of substrate cholesterol from the outer mitochondrial membrane to the cholesterol side chain cleavage enzyme system on the inner membrane. A recombinant StAR protein lacking
Chih-Hsien Chin et al.
The Chinese journal of physiology, 51(1), 54-61 (2008-06-17)
We report production of a polyclonal antibody against the StAR (steroidogenic acute regulatory) protein of steroidogenic cells and immunohistochemistry (IHC) staining of bovine adrenal gland tissue available in paraffin block. The epitope-specific polyclonal antibody was produced in a rabbit immunized

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