所有图片(1)
别名:
5′-[（3-氨丙基）硫代]-5′-脱氧腺苷, S-腺苷-3-硫代丙胺, dc-SAH, dcAdoHcy, 脱羧基S-腺苷-L-高半胱氨酸
经验公式（希尔记法）:
C13H20N6O3S
推荐产品
质量水平
检测方案
≥98.0% (HPLC)
形式
powder
储存温度
2-8°C
SMILES字符串
NCCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23
InChI
1S/C13H20N6O3S/c14-2-1-3-23-4-7-9(20)10(21)13(22-7)19-6-18-8-11(15)16-5-17-12(8)19/h5-7,9-10,13,20-21H,1-4,14H2,(H2,15,16,17)/t7-,9-,10-,13-/m1/s1
InChI key
FUSRAALGPJJIRO-QYVSTXNMSA-N
应用
S-(5′-腺苷)-3-硫代丙胺已被用作校准溶液，用于人尿液样品固相提取研究的加标。它还被用作毛细管电泳(CE)和胶束电动色谱(MEKC)中的分析物。
生化/生理作用
S-(5′-腺苷)-3-硫丙胺或 S-腺苷-L-高半胱氨酸包含碱基、糖或氨基酸。它作为亚精胺合成酶和精胺合成酶的抑制剂。
包装
无底玻璃瓶。内含物装在插入的融合锥内。
其他说明
这种脱羧的S-腺苷-L-蛋氨酸是多胺生物合成中的重要代谢物，充当丙胺转移酶（如精胺合酶和亚精胺合酶）的氨丙基供体。
警示用语：
Danger
危险声明
预防措施声明
危险分类
Acute Tox. 2 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Jolita Sečkutė et al.
Protein science : a publication of the Protein Society, 20(11), 1836-1844 (2011-09-08)
Aminopropyltransferases are essential enzymes that form polyamines in eukaryotic and most prokaryotic cells. Spermidine synthase (SpdS) is one of the most well-studied enzymes in this biosynthetic pathway. The enzyme uses decarboxylated S-adenosylmethionine and a short-chain polyamine (putrescine) to make a
Purification of spermidine synthase from rat ventral prostate by affinity chromatography on immobilized S-adenosyl(5')-3-thiopropylamine.
K Samejima et al.
Archives of biochemistry and biophysics, 216(1), 213-222 (1982-06-01)
Isolation of S-adenosyl-3-thiopropylamine.
S Ito
Methods in enzymology, 94, 463-464 (1983-01-01)
Alexander Vladimirovich Ivanov et al.
Electrophoresis, 41(3-4), 209-214 (2019-11-30)
A new approach for direct determination of S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), and methylthioadenosine (MTA) in urine was developed based on MEKC by using SDS modified with isobutanol in the presence of PEG-300. Analytes were first extracted with grafted phenylborononic acid.
H Hibasami et al.
The Biochemical journal, 187(2), 419-428 (1980-05-01)
1. S-Adenosyl-l-methionine, S-adenosyl-l-homocysteine, 5'-methylthioadenosine and a number of analogues having changes in the base, sugar or amino acid portions of the molecule were tested as potential inhibitors of spermidine synthase and spermine synthase from rat ventral prostate. 2. S-Adenosyl-l-methionine was
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