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生物来源
synthetic
方案
≥75% (TLC)
表单
crystalline
官能团
carboxylic acid
脂质类型
phosphoglycerides
储存温度
−20°C
SMILES字符串
[Na+].CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC
InChI
1S/C42H82NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h38-39H,3-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/t38-,39+;/m1./s1
InChI key
SJRBMGBLPUBGJL-MBAWARMDSA-M
应用
在胆固醇-磷脂混合物的相变研究中，胆固醇在凝胶相中与DSPS的混溶性要比液晶相中弱得多；最高50 mol％的胆固醇并不能消除烃链熔融相变。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Filippo Caschera et al.
PloS one, 5(1), e8546-e8546 (2010-01-06)
We consider the problem of optimizing a liposomal drug formulation: a complex chemical system with many components (e.g., elements of a lipid library) that interact nonlinearly and synergistically in ways that cannot be predicted from first principles. The optimization criterion
Jing Song et al.
Journal of applied biomaterials & functional materials, 18, 2280800020942712-2280800020942712 (2020-11-06)
A neurodegenerative disorder, glaucoma is a leading cause of blindness in the world. The conventional treatment strategies do not allow the significant penetration of the drug in the cornea. Therefore, we prepare a brinzolamide (Brz) loaded core-shell nanoparticles (NPs) to
Richard H Carson et al.
Journal of lipid research, 58(9), 1884-1892 (2017-07-27)
Compartmentalization of metabolism into specific regions of the cell, tissue, and organ is critical to life for all organisms. Mass spectrometric imaging techniques have been valuable in identifying and quantifying concentrations of metabolites in specific locations of cells and tissues
Kouhei Ohya et al.
Antimicrobial agents and chemotherapy, 63(4) (2019-02-06)
The present study aimed to clarify the mechanism underlying the high distribution of lascufloxacin in epithelial lining fluid (ELF). Involvement of transporters was examined by transcellular transport across Calu-3 and transporter-overexpressing cells; the binding of lascufloxacin to ELF components was
Monika Naumowicz et al.
Bioorganic chemistry, 92, 103242-103242 (2019-09-09)
Biological membranes are one of the most important elements of living cells determining their permeability to the active compounds. Still, little is known about the drug-membrane interactions in terms of pharmacological properties of potential drugs. Chemoprevention based on natural compounds
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