所有图片(1)
别名:
Tramadol HCl, (±)-cis-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride
经验公式（希尔记法）:
C16H25NO2 · HCl
CAS号:
分子量:
299.84
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.25
推荐产品
检测方案
≥99.0% (HPLC)
形式
powder
药品控制
USDEA Schedule IV
mp
178-181 °C
SMILES字符串
Cl.COc1cccc(c1)[C@@]2(O)CCCC[C@@H]2CN(C)C
InChI
1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1
InChI key
PPKXEPBICJTCRU-XMZRARIVSA-N
正在寻找类似产品? 访问 产品对比指南
应用
Tramadol hydrochloride has been used to study the tramadol biosynthesis route in plants.
生化/生理作用
Tramadol hydrochloride (HCl) inhibits the reuptake of norepinephrine and serotonin in μ-opioid receptors in rat models in vitro.
Opioid analgesic; P450 substrate.
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Aquatic Chronic 2 - STOT SE 3
靶器官
Central nervous system
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
监管及禁止进口产品
B Driessen et al.
British journal of pharmacology, 108(3), 806-811 (1993-03-01)
1. The centrally acting analgesic, tramadol, has low affinity for opioid receptors and therefore presumably other mechanisms of analgesic action. Neurotransmitter release and uptake experiments were used to characterize the effects of tramadol on the central noradrenergic and dopaminergic systems.
Howard S Smith
Mayo Clinic proceedings, 84(7), 613-624 (2009-07-02)
Clinicians understand that individual patients differ in their response to specific opioid analgesics and that patients may require trials of several opioids before finding an agent that provides effective analgesia with acceptable tolerability. Reasons for this variability include factors that
Arshi Kizilbash et al.
Journal of pain research, 7, 149-161 (2014-04-09)
Patients with chronic non-malignant pain report impairments of physical, social, and psychological well-being. The goal of pain management should include reducing pain and improving quality of life. Patients with chronic pain require medications that are able to provide adequate pain
Emrah Yuruk et al.
Journal of endourology, 29(4), 463-467 (2014-10-01)
To compare the outcomes of these minimally invasive procedures in this patient population. The database of our institution has been retrospectively reviewed, and medical records of urolithiasis patients with a solitary kidney who underwent flexible ureteroscopy (F-URS) or extracorporeal shock
Katarzyna M Romek et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(27), 8296-8301 (2015-06-25)
Tramadol, previously only known as a synthetic analgesic, has now been found in the bark and wood of roots of the African medicinal tree Nauclea latifolia. At present, no direct evidence is available as to the biosynthetic pathway of its
Chromatograms
application for HPLC我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门