所有图片(1)
别名:
(S)-2,3-环氧-2,3-二氢角鲨烯, (S)-22,23-环氧-2,6,10,15,19,23-六甲基-2,6,10,14,18-二十四碳五烯, (S)-角鲨烯 2,3-氧化物, (S)-角鲨烯 2,3-环氧化物
经验公式（希尔记法）:
C30H50O
推荐产品
质量水平
检测方案
≥97.5% (HPLC)
形式
liquid
光学纯度
enantiomeric excess: ≥90.0%
适用性
conforms to structure for Proton NMR spectrum
储存温度
−20°C
SMILES字符串
CC1(C)O[C@H]1CC/C(C)=C/CC/C(C)=C/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C
InChI
1S/C30H50O/c1-24(2)14-11-17-27(5)20-12-18-25(3)15-9-10-16-26(4)19-13-21-28(6)22-23-29-30(7,8)31-29/h14-16,20-21,29H,9-13,17-19,22-23H2,1-8H3/b25-15+,26-16+,27-20+,28-21+/t29-/m0/s1
InChI key
QYIMSPSDBYKPPY-RSKUXYSASA-N
应用
- Schizophrenic behavior of 2,3-Oxidosqualene Sterol Cyclase from pig liver towards 2,3-oxidosqualene analogues. Alain Krief and colleagues discuss the variable catalytic behaviors of oxidosqualene cyclase when interacting with different oxidosqualene analogues, suggesting implications for sterol production efficiency and specificity (Krief et al., 2021).
生化/生理作用
(S)-2,3-环氧角鲨烯是许多代谢途径的中间产物，如类固醇生物合成、倍半萜和三萜类生物合成、植物次生代谢物生物合成、萜类和类固醇生物合成、植物激素生物合成、次生代谢物生物合成以及抗生素生物合成。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Dorianne A Castillo et al.
Journal of the American Chemical Society, 135(15), 5885-5894 (2013-04-11)
Plants allocate an estimated 15-25% of their proteome to specialized metabolic pathways that remain largely uncharacterized. Here, we describe a genome mining strategy for exploring such unknown pathways and demonstrate this approach for triterpenoids by functionally characterizing three cytochrome P450s
Enzymatic cyclization of squalene and oxidosqualene to sterols and triterpenes.
Abe, I., et al.
Chemical Reviews, 93, 2189-2206 (1993)
Z Shi et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(15), 7370-7374 (1994-07-19)
The ERG7 gene encoding oxidosqualene-lanosterol cyclase [(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol forming), EC 5.4.99.7] from Saccharomyces cerevisiae has been cloned by genetic complementation of a cyclase-deficient erg7 strain. The DNA sequence of this gene has been determined and found to contain
Xudong Han et al.
Frontiers in oncology, 10, 1549-1549 (2020-10-20)
Glioblastoma, also known as glioblastoma multiforme (GBM), is the most malignant form of glioma and represents 81% of malignant brain and central nervous system (CNS) tumors. Like most cancers, GBM causes metabolic recombination to promote cell survival, proliferation, and invasion
Katherine A Mattos et al.
Cellular microbiology, 16(6), 797-815 (2014-02-21)
We recently showed that Mycobacterium leprae (ML) is able to induce lipid droplet formation in infected macrophages. We herein confirm that cholesterol (Cho) is one of the host lipid molecules that accumulate in ML-infected macrophages and investigate the effects of
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