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生物来源
rabbit
质量水平
100
500
偶联物
unconjugated
抗体形式
Ig fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
表单
buffered aqueous solution
种属反应性
human
包装
vial of 0.1 mL concentrate (413A-14)
vial of 0.5 mL concentrate (413A-15)
bottle of 1.0 mL predilute (413A-17)
vial of 1.0 mL concentrate (413A-16)
bottle of 7.0 mL predilute (413A-18)
制造商/商品名称
Cell Marque®
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
控制
embryonal carcinoma, yolk sac tumor
运输
wet ice
储存温度
2-8°C
可视化
membranous
基因信息
human ... SLC2A3(6515)
一般描述
Glucose transporter membrane 3 (GLUT3) is known as a solute carrier family 2 (facilitated glucose transporter) member 3 and represents a membrane bound glucose transporter. In one study scientists, using immunoprecipitation and western blot technologies, detected GLUT3 expression in spermatozoa of testis and brain but not in other types of tissue. In-house research via immunohistochemistry confirmed GLUT3 expression in testis/spermatozoa, but no GLUT3 was detected in brain. In a study conducted by Howitt BE et. al. anti-GLUT3 demonstrated membranous staining of seminoma cells in 44 cases (65%) of total 67 specimens. In addition, anti-GLUT3 labeled embryonal carcinoma (20/20) and yolk sac tumor (8/8) with 100% sensitivity.GLUT3 is not expressed in non-germ cell tumors such as leydig cell tumor and adenomatoid tumor.Spermatocytic seminoma, choriocarcinoma, and immature teratoma are also negative for GLUT3. Therefore, anti-GLUT3 is a very useful IHC marker to include in a panel for identification of germ cell tumors.
质量
 IVD |  IVD |  IVD |  RUO |
联系
GLUT3 Positive Control Slides, Product No. 413S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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法规信息
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历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Brooke E Howitt et al.
Applied immunohistochemistry & molecular morphology : AIMM, 21(5), 401-407 (2013-01-25)
Testicular germ cell tumors (TGCT) are the most common type of testicular tumor and encompass different histologic types that greatly influence treatment and prognosis. Immunohistochemical studies may be required for accurate classification, particularly when these tumors present at extragonadal sites
R S Haber et al.
Endocrinology, 132(6), 2538-2543 (1993-06-01)
The tissue distribution of the GLUT3 glucose transporter protein was examined in human tissues using a rabbit antiserum directed against the C-terminal peptide sequence of human GLUT3. This anti-serum was shown to recognize the human GLUT3 protein in Chinese hamster
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