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Merck
CN

40667

Supelco

Zinpyr-1

≥95.0% (HPCE)

别名:

4′,5′-Bis[bis(2-pyridylmethyl)aminomethyl]-2′,7′-dichlorofluorescein

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About This Item

经验公式(希尔记法):
C46H36Cl2N6O5
分子量:
823.72
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:

检测方案

≥95.0% (HPCE)

荧光

λex 492 nm; λem 527 nm in PBS, Zn2+

储存温度

−20°C

SMILES字符串

OC(=O)c1ccccc1C2=C3C=C(Cl)C(=O)C(CN(Cc4ccccn4)Cc5ccccn5)=C3Oc6c(CN(Cc7ccccn7)Cc8ccccn8)c(O)c(Cl)cc26

InChI

1S/C46H36Cl2N6O5/c47-39-21-35-41(33-15-1-2-16-34(33)46(57)58)36-22-40(48)43(56)38(28-54(25-31-13-5-9-19-51-31)26-32-14-6-10-20-52-32)45(36)59-44(35)37(42(39)55)27-53(23-29-11-3-7-17-49-29)24-30-12-4-8-18-50-30/h1-22,55H,23-28H2,(H,57,58)

InChI key

NKEYRLVORYSIBB-UHFFFAOYSA-N

应用

Suitable for the fluorometric detection of zinc.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

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Eiko Hayase et al.
The Journal of experimental medicine, 214(12), 3507-3518 (2017-10-27)
The intestinal microbial ecosystem is actively regulated by Paneth cell-derived antimicrobial peptides such as α-defensins. Various disorders, including graft-versus-host disease (GVHD), disrupt Paneth cell functions, resulting in unfavorably altered intestinal microbiota (dysbiosis), which further accelerates the underlying diseases. Current strategies
Vladislav Strmiska et al.
Molecular oncology, 13(5), 1002-1017 (2019-01-11)
DNA hypermethylation is one of the most common epigenetic modifications in prostate cancer (PCa). Several studies have delineated sarcosine as a PCa oncometabolite that increases the migration of malignant prostate cells while decreasing their doubling time. Here, we show that
Haizhen Zhang et al.
Plant signaling & behavior, 14(10), e1654353-e1654353 (2019-08-14)
Heat shock transcription factors (HSFs) play pivotal roles in various abiotic stresses. However, only one of the studies on HSFs that participated in excess zinc (Zn) stress in our previous study in Populus ussuriensis. Here, overexpression of P. trichocarpa PtHSFA4a
Eugene Roscioli et al.
American journal of physiology. Lung cellular and molecular physiology, 313(3), L453-L465 (2017-06-10)
The proper regulation of zinc (Zn) trafficking proteins and the cellular distribution of Zn are critical for the maintenance of autophagic processes. However, there have been no studies that have examined Zn dyshomeostasis and the disease-related modulation of autophagy observed
Marc Diedisheim et al.
Molecular metabolism, 10, 74-86 (2018-02-24)
Dedifferentiation could explain reduced functional pancreatic β-cell mass in type 2 diabetes (T2D). Here we model human β-cell dedifferentiation using growth factor stimulation in the human β-cell line, EndoC-βH1, and human pancreatic islets. Fibroblast growth factor 2 (FGF2) treatment reduced

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