跳转至内容
Merck
CN
所有图片(1)

文件

安全信息

404R-1

Sigma-Aldrich

C4d (SP91) Rabbit Monoclonal Antibody

登录查看公司和协议定价


About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

SP91, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形式

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (404R-14)
vial of 0.5 mL concentrate (404R-15)
bottle of 1.0 mL predilute (404R-17)
vial of 1.0 mL concentrate (404R-16)
bottle of 7.0 mL predilute (404R-18)

制造商/商品名称

Cell Marque

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

同位素/亚型

IgG

控制

lymph node, tonsil

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic, membranous

基因信息

human ... C4B(721)

一般描述

Acute humoral rejection is mediated by antibodies to the donor endothelium that activates the classical complement pathway. This leads to a number of split products of complement proteins. C4d is a fragment of C4 complement released during activation of the classic complement pathway by the antigen-antibody complex. C4d deposits in peritubular capillaries and is regarded as an indirect sign of an antibody response. C4d can be a useful tool for indicating acute renal allograft rejection.

质量


IVD

IVD

IVD

RUO

联系

C4d Positive Control Slides, Product No. 404S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our 产品选型工具.

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Liise K Kayler et al.
Transplantation, 85(6), 813-820 (2008-03-25)
Focal PTC C4d staining in acute renal allograft rejection has not been studied extensively. Renal allograft biopsies performed after October 2003, representing the first episode of acute rejection (AR) in recipients with > or = 12 months follow-up postbiopsy, were
Christian A Seemayer et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 22(2), 568-576 (2006-12-14)
Detection of C4d along peritubular capillaries (PTC) in renal allograft biopsies is an independent prognostic marker of poor long-term graft survival. It is typically associated with circulating donor-specific antibodies. Since only little information is available on the best technique to
Gyongyi M Nadasdy et al.
Human pathology, 36(11), 1178-1185 (2005-11-02)
Detection of peritubular capillary (PTC) C4d deposition in tissue sections of renal allograft biopsies became an important aid in the diagnosis of antibody-mediated rejection. Pathologists in many major transplant centers now routinely stain renal allograft biopsies for C4d. Currently, there
Dorothée Bouron-Dal Soglio et al.
Human pathology, 39(7), 1103-1110 (2008-06-24)
C4d is a marker of the activated complement cascade used to assess the humoral component of rejection, mostly in kidney allograft transplants. The role of C4d deposition has recently been addressed in hepatic allograft but has never been tested in
Chen Jianghua et al.
Clinical transplantation, 19(6), 785-791 (2005-11-30)
To determine the diagnostic and clinical significance of C4d accumulation in renal allografts followed by acute rejection. A total of 158 graft biopsies performed from December 1997 to December 2002 were classified, according to the Banff-97 criteria, into hyperacute rejection

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门